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This article is cited in 13 scientific papers (total in 13 papers)
Sulfonyl modulators of serotonin 5-HT$_{6}$ receptors and their pharmacophore models
A. V. Ivachtchenkoabc a Chemical Diversity Research Institute
b ChemDiv, Inc.
c Aniveuro Pharmaceuticals, Inc., San Diego, CA, USA
Abstract:
The data on the syntheses of serotonin 5-HT$_{6}$ receptor modulators published in recent years are surveyed. Modulators with high affinity to 5-HT$_{6}$ receptors with different selectivity degrees ranging from highly selective to semi selective and multimodal are described. The results of clinical trials of the most promising 5-HT$_{6}$ receptor modulators that arouse most interest in medicinal chemists are also described.
Bibliography — 128 references.
Received: 27.01.2013
Citation:
A. V. Ivachtchenko, “Sulfonyl modulators of serotonin 5-HT$_{6}$ receptors and their pharmacophore models”, Usp. Khim., 83:5 (2014), 439–473; Russian Chem. Reviews, 83:5 (2014), 439–473
Linking options:
https://www.mathnet.ru/eng/rcr698https://doi.org/10.1070/RC2014v083n05ABEH004371 https://www.mathnet.ru/eng/rcr/v83/i5/p439
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