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This article is cited in 57 scientific papers (total in 57 papers)
Multifunctional biocompatible coatings on magnetic nanoparticles
A. V. Bychkova, O. N. Sorokina, M. A. Rosenfeld, A. L. Kovarskii Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow
Abstract:
Methods for coating formation on magnetic nanoparticles used in biology and medicine are considered. Key requirements to the coatings are formulated, namely, biocompatibility, stability, the possibility of attachment of pharmaceutical agents, and the absence of toxicity. The behaviour of nanoparticle/coating nanosystems in the body including penetration through cellular membranes and the excretion rates and routes is analyzed. Parameters characterizing the magnetic properties of these systems and their magnetic controllability are described. Factors limiting the applications of magnetically controlled nanosystems for targeted drug delivery are discussed. The bibliography includes 405 references.
Received: 19.10.2011
Citation:
A. V. Bychkova, O. N. Sorokina, M. A. Rosenfeld, A. L. Kovarskii, “Multifunctional biocompatible coatings on magnetic nanoparticles”, Usp. Khim., 81:11 (2012), 1026–1050; Russian Chem. Reviews, 81:11 (2012), 1026–1050
Linking options:
https://www.mathnet.ru/eng/rcr616https://doi.org/10.1070/RC2012v081n11ABEH004280 https://www.mathnet.ru/eng/rcr/v81/i11/p1026
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