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Russian Chemical Reviews, 2021, Volume 90, Issue 4, Pages 451–487
DOI: https://doi.org/10.1070/RCR4977 (Mi rcr4340) 		 
This article is cited in 22 scientific papers (total in 22 papers)

Progress in the medical chemistry of organoboron compounds

A. N. Tevyashovaa, M. V. Chudinovb

a G. F. Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, Moscow
b MIREA — Russian Technological University, Moscow
English full-text Citations (22)
DOI: https://doi.org/10.1070/RCR4977
Abstract: The review aims to draw attention to the latest advances in the organoboron chemistry and therapeutic use of organoboron compounds. The synthetic strategies towards boron-containing compounds with proven in vitro and/or in vivo biological activities, including derivatives of boronic acids, benzoxaboroles, benzoxaborines and benzodiazaborines, are summarized. Approaches to the synthesis of hybrid structures containing an organoboron moiety as one of the pharmacophores are considered, and the effect of this modification on the pharmacological activity of the initial molecules is analyzed. On the basis of analysis of the published data, the most promising areas of research in the field of organoboron compounds are identified, including the latest methods of synthesis, modification and design of effective therapeutic agents.
The bibliography includes 246 references.
Keywords: boronic acids, benzoxaboroles, benzoxaborines, benzodiazaborines, carboranes, boron clusters, borylation, drug design, biological activity, drug delivery systems, boron neutron capture therapy.
Received: 06.07.2020
Russian version:
Uspekhi Khimii, 2021, Volume 90, Issue 4, Pages 451–487
DOI: https://doi.org/10.1070/RCR4977
Bibliographic databases:
Document Type: Article
Language: English
Original paper language: Russian
Citation: A. N. Tevyashova, M. V. Chudinov, “Progress in the medical chemistry of organoboron compounds”, Usp. Khim., 90:4 (2021), 451–487; Russian Chem. Reviews, 90:4 (2021), 451–487
Citation in format AMSBIB
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\paper Progress in the medical chemistry of organoboron compounds
\jour Usp. Khim.
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\issue 4
\pages 451--487
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\crossref{https://doi.org/10.1070/RCR4977}
\adsnasa{https://adsabs.harvard.edu/cgi-bin/bib_query?2021RuCRv..90..451T}
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\transl
\jour Russian Chem. Reviews
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\vol 90
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\pages 451--487
\crossref{https://doi.org/10.1070/RCR4977}
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  • https://doi.org/10.1070/RCR4977
  • https://www.mathnet.ru/eng/rcr/v90/i4/p451
    • This publication is cited in the following 22 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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