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This article is cited in 12 scientific papers (total in 12 papers)
Arbidol: a quarter-century later. Past, present and future of the original Russian antiviral
Konstantin V. Balakinab, Rosanna Filosacde, Sergey N. Lavrenovf, Arthur S. Mkrtchyang, Maxim B. Nawrozkijg, Ivan A. Novakovg a Kazan (Volga Region) Federal University
b I. M. Sechenov First Moscow State Medical University
c Department of Experimental Medicine, Section of Biotechnology, University of Campania "Luigi Vanvitelli", Italy
d Consorzio Sannio Tech, Italy
e Institute of Food Sciences, National Research Council, Italy
f Gause Institute of New Antibiotics, Moscow
g Volgograd State Technical University
Abstract:
The present review relates to the synthesis and structure-activity relationship studies of Arbidol and its structural analogues. The latter are roughly divided into several unequal parts: indole- and benzofuran-based compounds, benzimidazole and imidazopyridine bioisosteres, and ring-expanded quinoline derivatives. Much attention is focused on various types of antiviral activity of the above-mentioned Arbidol congeners, as well as of the parent compound itself. Features of Arbidol synthesis and metabolic changes are also discussed.
Bibliography — 166 references.
Received: 18.10.2017
Citation:
Konstantin V. Balakin, Rosanna Filosa, Sergey N. Lavrenov, Arthur S. Mkrtchyan, Maxim B. Nawrozkij, Ivan A. Novakov, “Arbidol: a quarter-century later. Past, present and future of the original Russian antiviral”, Usp. Khim., 87:6 (2018), 509–552; Russian Chem. Reviews, 87:6 (2018), 509–552
Linking options:
https://www.mathnet.ru/eng/rcr4211https://doi.org/10.1070/RCR4791 https://www.mathnet.ru/eng/rcr/v87/i6/p509
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