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This article is cited in 82 scientific papers (total in 82 papers)
ortho-Quinone methides as key intermediates in cascade heterocyclizations
D. V. Osipova, V. A. Osyaninba, Yu. N. Klimochkina a Samara State Technical University
b Peoples Friendship University of Russia, Moscow
Abstract:
Development of new methods of heterocyclic synthesis is still a topical issue. In this connection, the trend related to the use of highly reactive o-quinone methides for the synthesis and functionalization of heterocycles appears rather promising. Since most of o-quinone methides are unstable, the choice of precursors and generation conditions is highly important for subsequent transformations involving them. Various methods of generation of o-quinone methides and cascade heterocyclizations in which the formation of these compounds is a key step are surveyed in the review. The trends of using o-quinone methides in the synthesis of various heterocycles are analyzed and the heterocyclization reactions involving these compounds are classified.
The bibliography includes 395 references.
Received: 02.07.2016
Citation:
D. V. Osipov, V. A. Osyanin, Yu. N. Klimochkin, “ortho-Quinone methides as key intermediates in cascade heterocyclizations”, Usp. Khim., 86:7 (2017), 625–687; Russian Chem. Reviews, 86:7 (2017), 625–687
Linking options:
https://www.mathnet.ru/eng/rcr4170https://doi.org/10.1070/RCR4679 https://www.mathnet.ru/eng/rcr/v86/i7/p625
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