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This article is cited in 11 scientific papers (total in 11 papers)
Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties
I. I. Popadyuka, O. V. Salomatinaa, N. F. Salakhutdinovab a N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistryof the Siberian Branch of Russian Academy of Sciences
b Novosibirsk State University
Abstract:
Data published in the period from 2000 to 2015 on chemical transformations of the major human bile acids (cholic, chenodeoxycholic, deoxycholic and lithocholic acids) and ursodeoxycholic acid are integrated and described systematically. Characteristic features of their structures, biosynthesis, main sources and biological functions are considered. The data on chemical transformations of the indicated bile acids include reactions involving modifications of the side chain or the steroid nucleus. The biological activities and applications of these derivatives are surveyed in brief. The bibliography includes 227 references.
Received: 11.05.2016
Citation:
I. I. Popadyuk, O. V. Salomatina, N. F. Salakhutdinov, “Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties”, Usp. Khim., 86:5 (2017), 388–443; Russian Chem. Reviews, 86:5 (2017), 388–443
Linking options:
https://www.mathnet.ru/eng/rcr4162https://doi.org/10.1070/RCR4683 https://www.mathnet.ru/eng/rcr/v86/i5/p388
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