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Russian Chemical Reviews, 2016, Volume 85, Issue 10, Pages 1056–1096
DOI: https://doi.org/10.1070/RCR4586 (Mi rcr4133) 		 
This article is cited in 16 scientific papers (total in 16 papers)

Dihydropyrimidin-$2(1H)$-one and its analogues as a platform for the design and synthesis of new biologically active compounds

O. P. Shkurko, T. G. Tolstikova, V. F. Sedova

N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistryof the Siberian Branch of Russian Academy of Sciences
English full-text Citations (16)
DOI: https://doi.org/10.1070/RCR4586
Abstract: The data published mainly over two past decades on various types of biological activity of 5-functionally substituted 3,4-dihydropyrimidin-2-ones and their analogues, 2-thiones and 2-imines, and more complex dihydropyrimidine derivatives are summarized. Apart from medicinal chemistry issues, including structure–activity relationships, the pharmacological profiles of the most promising derivatives and the routes for further structural modification of known chemical compounds are discussed in general terms. Examples of potential uses of new compounds in medicine as single pharmaceutical agents and as parts of compositions are given.
The bibliography includes 334 references.
Funding agency Grant number
Russian Academy of Sciences - Federal Agency for Scientific Organizations 0302-2015-0001
Received: 02.07.2015
Russian version:
Uspekhi Khimii, 2016, Volume 85, Issue 10, Pages 1056–1096
DOI: https://doi.org/10.1070/RCR4586
Bibliographic databases:
Document Type: Article
Language: English
Original paper language: Russian
Citation: O. P. Shkurko, T. G. Tolstikova, V. F. Sedova, “Dihydropyrimidin-$2(1H)$-one and its analogues as a platform for the design and synthesis of new biologically active compounds”, Usp. Khim., 85:10 (2016), 1056–1096; Russian Chem. Reviews, 85:10 (2016), 1056–1096
Citation in format AMSBIB
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\paper Dihydropyrimidin-$2(1H)$-one and its analogues as a platform for the design and synthesis of new biologically active compounds
\jour Usp. Khim.
\yr 2016
\vol 85
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\pages 1056--1096
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\crossref{https://doi.org/10.1070/RCR4586}
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\jour Russian Chem. Reviews
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\pages 1056--1096
\crossref{https://doi.org/10.1070/RCR4586}
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    • This publication is cited in the following 16 articles:
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