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This article is cited in 10 scientific papers (total in 10 papers)
Biomedical applications of capillary electrophoresis
L. A. Kartsova, E. A. Bessonova Institute of Chemistry, St. Petersburg State University
Abstract:
The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed.
The bibliography includes 173 references.
Received: 04.08.2014
Citation:
L. A. Kartsova, E. A. Bessonova, “Biomedical applications of capillary electrophoresis”, Usp. Khim., 84:8 (2015), 860–874; Russian Chem. Reviews, 84:8 (2015), 860–874
Linking options:
https://www.mathnet.ru/eng/rcr4064https://doi.org/10.1070/RCR4492 https://www.mathnet.ru/eng/rcr/v84/i8/p860
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