Abstract:
Basic approaches to the design of targeted drugs for the treatment of human malignant tumours have been considered. The stages of the development of these approaches have been described in detail and theoretically substantiated, and basic experimental results have been reported. Considerable attention is paid to the general characteristic of nanopharmacological drugs and to the description of mechanisms of cellular interactions with nanodrugs. The potentialities and limitations of application of nanodrugs for cancer therapy and treatment of other diseases have been considered. The use of nanodrugs conjugated with vector molecules seems to be the most promising trend of targeted therapy of malignant tumours.
The bibliography includes 122 references.
Received: 20.05.2014
Bibliographic databases:
Document Type:
Article
Language: English
Original paper language: Russian
Citation:
E. S. Severin, “New approaches to targeted drug delivery to tumour cells”, Russian Chem. Reviews, 84:1 (2015), 43–60
\Bibitem{Sev15}
\by E.~S.~Severin
\paper New approaches to targeted drug delivery to tumour cells
\jour Russian Chem. Reviews
\yr 2015
\vol 84
\issue 1
\pages 43--60
\mathnet{http://mi.mathnet.ru/eng/rcr4028}
\crossref{https://doi.org/10.1070/RCR4468}
\isi{https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Publons&SrcAuth=Publons_CEL&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=000349382400004}
\elib{https://elibrary.ru/item.asp?id=22662157}
\scopus{https://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84922512088}
Linking options:
https://www.mathnet.ru/eng/rcr4028
https://doi.org/10.1070/RCR4468
https://www.mathnet.ru/eng/rcr/v84/i1/p43
This publication is cited in the following 18 articles:
S. V. Shilova, G. M. Mirgaleev, V. P. Barabanov, Polym. Sci. Ser. A, 64:5 (2022), 447
N. G. Yabbarov, M. D. Mollaev, A. I. Zabolotskii, D. A. Mazalev, N. V. Gorokhovets, M. B. Sokol, M. R. Mollaeva, M. V. Fomicheva, A. B. Pshenichnikova, E. D. Nikolskaya, Appl Biochem Microbiol, 58:8 (2022), 899
M. B. Sokol, Yu. V. Sycheva, N. G. Yabbarov, A. I. Zabolotskii, M. D. Mollaev, M. R. Faustova, O. G. Tereshchenko, M. V. Fomicheva, E. D. Nikol'skaya, Pharm. Chem. J., 54:8 (2020), 846–850
N. M. Selivanova, A. T. Gubaidullin, Yu. G. Galyametdinov, J. Phys. Chem. B, 124:13 (2020), 2715–2722
R. Yu. Yakovlev, P. G. Mingalev, N. B. Leonidov, G. V. Lisichkin, Pharm. Chem. J., 54:4 (2020), 389–403
S. V. Shilova, G. M. Mirgaleev, A. Ya. Tret'yakova, V. P. Barabanov, Polym. Sci. Ser. A, 62:6 (2020), 630–635
G. Gocheva, A. Ivanova, Mol. Pharm., 16:8 (2019), 3293–3321
E. D. Nikolskaya, M. R. Faustova, M. D. Mollaev, O. A. Zhunina, M. B. Sokol, N. G. Yabbarov, N. V. Gukasova, A. V. Lobanov, V. I. Shvets, E. S. Severin, Russ. Chem. Bull., 67:4 (2018), 747–756
A. F. Mironov, K. A. Zhdanova, N. A. Bragina, Russ. Chem. Rev., 87:9 (2018), 859–881
N. M. Selivanova, A. T. Gubaidullin, Yu. G. Galyametdinov, Liq. Cryst. Appl., 18:3 (2018), 6–13
E. D. Nikolskaya, O. A. Zhunina, E. A. Vasilenko, N. G. Yabbarov, O. G. Tereshchenko, M. B. Sokol, V. I. Popenko, E. S. Severin, Russ. J. Bioorg. Chem., 43:5 (2017), 552–560
E. K. Beloglazkina, A. G. Majouga, N. V. Zyk, Ya. A. Ivanenkov, S. Yu. Maklakova, A. G. Nazarenko, A. G. Tonevitsky, V. È. Kotelianski, Russ. Chem. Rev., 86:8 (2017), 750–776
E. D. Nikolskaya, O. A. Zhunina, N. G. Yabbarov, O. G. Tereshchenko, A. V. Godovannyy, N. V. Gukasova, E. S. Severin, Russ. J. Bioorg. Chem., 43:3 (2017), 278–285
E. D. Nikolskaya, O. A. Zhunina, N. G. Yabbarov, V. I. Shvets, B. I. Krugliy, E. S. Severin, Dokl. Biochem. Biophys., 473:1 (2017), 148–150
V. I. Shvets, G. M. Sorokoumova, A. I. Lyutik, A. B. Pshenichnikova, D. I. Prokhorov, N. V. Rukosueva, A. G. Yakovenko, A. M. Khort, S. N. Chvalun, Yu. M. Krasnopolsky, V. Yu. Balabanyan, E. S. Severin, A. A. Kubatiev, Fine Chem. Tech., 12:6 (2017), 5
Citation in format AMSBIB
Contact us: