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This article is cited in 13 scientific papers (total in 13 papers)
Advances in the Search for Medicinal Drugs Based on γ-Aminobutyric Acid
V. M. Kopelevich NII Vitamins, Moscow
Abstract:
Problems associated with the search for new psychotropic agents based on γ-aminobutyric acid – a mediator of central inhibition – are examined, the principles of the rational synthesis of new medicinal drugs in the series of γ-aminobutyric acid derivatives are discussed, and methods for their chemical synthesis are described. Data are presented on the conformation of γ-aminobutyric acid and the structure of its receptor; certain features of the relation between structure and biological activity in the above series of compounds are considered. The bibliography includes 178 references.
Citation:
V. M. Kopelevich, “Advances in the Search for Medicinal Drugs Based on γ-Aminobutyric Acid”, Usp. Khim., 48:7 (1979), 1273–1296; Russian Chem. Reviews, 48:7 (1979), 679–691
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https://www.mathnet.ru/eng/rcr3150https://doi.org/10.1070/RC1979v048n07ABEH002392 https://www.mathnet.ru/eng/rcr/v48/i7/p1273
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