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Russian Chemical Reviews, 1975, Volume 44, Issue 11, Pages 993–998
DOI: https://doi.org/10.1070/RC1975v044n11ABEH002474
(Mi rcr2849)
 

The Mechanism of the Excitability of Biological Membranes

Yu. A. Chizmadzhev, V. F. Pastushenko, V. S. Markin

Frumkin Institute of Electrochemistry of the USSR Academy of Sciences, Moscow
Abstract: The phenomenology of the excitation of a cell membrane is described. It is shown that, in the adsorption inhibition of a mobile transferring agent, the descending branch of the voltage–current characteristic can be obtained. The Hodgkin–Huxley model is interpreted in terms of ionic channels and the statistical properties of such a system are examined. In particular, the spectrum of the electrical fluctuations of potassium channels is analysed. Experiments in which "gating currents" were measured are briefly described and interpreted in terms of the cooperative dipole model.
The bibliography includes 16 references.
Russian version:
Uspekhi Khimii, 1975, Volume 44, Issue 11, Pages 2078–2087
DOI: https://doi.org/10.1070/RC1975v044n11ABEH002474
Bibliographic databases:
Document Type: Article
UDC: 541.13-534.121.2
Language: English
Original paper language: Russian


Citation: Yu. A. Chizmadzhev, V. F. Pastushenko, V. S. Markin, “The Mechanism of the Excitability of Biological Membranes”, Usp. Khim., 44:11 (1975), 2078–2087; Russian Chem. Reviews, 44:11 (1975), 993–998
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