Condensation of Oxazoles with Dienophiles – a New Method for the Synthesis of Pyridine Bases

The condensation of oxazoles with dienophiles is of the diene synthesis type, the final reaction products being substituted pyridine bases. The review deals with the literature data concerning the preparative applications of the condensation and the elucidation of the theoretical features of this process. In conclusion of the review, the application of heterodiene synthesis with participation of oxazoles in the preparation of vitamin B₆ and its analogues is discussed. The bibliography comprises 38 references.