|
This article is cited in 9 scientific papers (total in 9 papers)
HIV-1 integrase inhibitors as new components of antiviral therapy
T. A. Prikazchikovaa, A. M. Sychevab, Yu. Yu. Agapkinab, D. A. Aleksandrova, M. B. Gottikha a Lomonosov Moscow State University, Belozersky Research Institute of Physico-Chemical Biology
b Lomonosov Moscow State University, Faculty of Chemistry
Abstract:
Structural and functional features of HIV-1 integrase are considered and the state of the art in the quest for effective inhibitors of this enzyme is reported. The major classes of integrase inhibitors with known mechanisms of action as well as their in vitro and in vivo inhibitory activities are presented.
Received: 24.01.2008
Citation:
T. A. Prikazchikova, A. M. Sycheva, Yu. Yu. Agapkina, D. A. Aleksandrov, M. B. Gottikh, “HIV-1 integrase inhibitors as new components of antiviral therapy”, Usp. Khim., 77:5 (2008), 445–459; Russian Chem. Reviews, 77:5 (2008), 421–434
Linking options:
https://www.mathnet.ru/eng/rcr225https://doi.org/10.1070/RC2008v077n05ABEH003779 https://www.mathnet.ru/eng/rcr/v77/i5/p445
|
Statistics & downloads: |
Abstract page: | 271 |
|