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This article is cited in 88 scientific papers (total in 88 papers)
Multicomponent reactions of isocyanides in the synthesis of heterocycles
A. V. Ivachtchenkoab, Ya. A. Ivanenkovb, V. M. Kysila, M. Yu. Krasavinb, A. P. Ilyinb a ChemDiv, Inc.
b Chemical Diversity Research Institute
Abstract:
The latest achievements in the field of isocyanide-based multicomponent reactions for the synthesis of heterocycles are generalized. The attention is focused on the intramolecular Ugi reactions of oxocarboxylic acids and the reactions of diaza nucleophiles developed in recent years. The data on the biological activities of the products are presented and the advantages of this method as a convenient and effective tool of medicinal chemistry are demonstrated.
Received: 10.07.2009
Citation:
A. V. Ivachtchenko, Ya. A. Ivanenkov, V. M. Kysil, M. Yu. Krasavin, A. P. Ilyin, “Multicomponent reactions of isocyanides in the synthesis of heterocycles”, Usp. Khim., 79:9 (2010), 861–893; Russian Chem. Reviews, 79:9 (2010), 787–817
Linking options:
https://www.mathnet.ru/eng/rcr132https://doi.org/10.1070/RC2010v079n09ABEH004086 https://www.mathnet.ru/eng/rcr/v79/i9/p861
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