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Special issue on laser biophotonics
Estimation of a minimum laser power with wavelengths of 1.47, 1.56, and 1.68 μm for efficient obliteration of varicose veins
N. Yu. Ignat'evaa, O. L. Zakharkinab, A. P. Sviridovb, K. V. Mazaishvilic, A. B. Shekhterd a Faculty of Chemistry, Lomonosov Moscow State University
b Institute of Photonic Technologies, Federal Research Centre ‘Crystallography and Photonics’, Russian Academy of Sciences, Troitsk, Moscow, Russia
c Medical Institute, Surgut State University, Surgut, Khanty-Mansiysk autonomous okrug – Yugra, Russia
d Institute for Regenerative Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Abstract:
Experiments modelling endovenous laser obliteration (EVLO) are performed. As a result, laser radiation powers Pc at which collagen denaturation, tissue necrosis, and vasa vasorum destruction occur throughout the entire venous-wall thickness and, at the same time, the surrounding tissues are not subjected to unnecessary heating, are found. The main criterion for determining Pc is the achievement of 100% denaturation of venous-wall proteins, confirmed by morphological and calorimetric analysis. The Pc values for laser wavelengths of 1.47, 1.56, and 1.68 mm are found to be 6.0 ± 0.2, 5.0 ± 0.2, and 6.0 ± 0.2 W, respectively. It is established for all wavelengths in use that the temperature of the external venous-wall surface reaches 91 ± 2 °C at the corresponding power Pc. We relate the dependence of Pc on the radiation wavelength to the formation of a coagulum on the optical fibre tip moving through a blood-filled vessel. The achievement of temperature necessary for coagulum formation is determined by the simultaneously occurring processes of energy absorption and its dissipation in the form of heat. These processes become more intense with an increase in the absorption coefficient of the medium. A mechanism is proposed to explain the relationship between the Pc value and laser wavelength, based on the influence of the absorption coefficient of medium (blood) on the temperature near the fibre tip.
Keywords:
laser heating, energy absorption and dissipation, venous wall, collagen denaturation, obliteration of varicose veins.
Received: 01.09.2021
Citation:
N. Yu. Ignat'eva, O. L. Zakharkina, A. P. Sviridov, K. V. Mazaishvili, A. B. Shekhter, “Estimation of a minimum laser power with wavelengths of 1.47, 1.56, and 1.68 μm for efficient obliteration of varicose veins”, Kvantovaya Elektronika, 52:1 (2022), 78–82 [Quantum Electron., 52:1 (2022), 78–82]
Linking options:
https://www.mathnet.ru/eng/qe17968 https://www.mathnet.ru/eng/qe/v52/i1/p78
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Abstract page: | 81 | Full-text PDF : | 6 | References: | 17 | First page: | 7 |
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