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Kvantovaya Elektronika, 2018, Volume 48, Number 5, Pages 481–486 (Mi qe16811)  

This article is cited in 4 scientific papers (total in 4 papers)

Laser medicine

Effect of laser UV radiation on the eye scleral tissue in patients with open-angle glaucoma

A. M. Razhevab, I. A. Iskakovc, D. S. Churkinad, A. M. Orishiche, N. A. Masloved, E. O. Tsibul'skayaed, A. A. Lomzovdf, O. V. Ermakovac, A. N. Trunovc, V. V. Chernykhc

a Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk
b Novosibirsk State Technical University
c Novosibirsk Branch of S.N. Fyodorov Eye Microsurgery Federal State Institution
d Novosibirsk State University
e Khristianovich Institute of Theoretical and Applied Mechanics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk
f Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk
References:
Abstract: We report the results of an experimental study of the effect of short-pulse laser UV radiation on the eye scleral tissue. As samples, we used isolated flaps of the eye scleral tissue from the patients with open-angle glaucoma of the second and third stages. The impact was implemented using the radiation of an excimer XeCl laser with a wavelength of 308 nm and a laser with a wavelength tunable within from 210 to 355 nm. Depending on the problem to be solved, the energy density on the surface of the irradiated tissue varied from a fraction of mJ cm-2 to 15 J cm-2. For the first time we studied the optical properties of the intraocular fluid in the UV and blue spectral range. The study of the ablation process under the action of radiation with a wavelength of 308 nm showed that the rate of material evaporation can vary within 25%–30% at an energy density above 7 J cm-2, depending on the glaucoma stage and the individual features of a patient. The excitation–emission matrices of laser-induced fluorescence (LIF) of the eye scleral tissue were studied experimentally using a laser with a wavelength tuned in the range 210–355 nm. We found the differences in the LIF spectra caused by the excitation wavelength and the openangle glaucoma stage.
Keywords: laser-induced fluorescence, effect of high-power laser UV radiation on biotissues, open-angle glaucoma, optical properties of biotissues, intraocular fluid, pulsed UV excimer laser.
Funding agency Grant number
Interdisciplinary integrated project 68
Received: 31.10.2017
Revised: 08.02.2018
English version:
Quantum Electronics, 2018, Volume 48, Issue 5, Pages 481–486
DOI: https://doi.org/10.1070/QEL16562
Bibliographic databases:
Document Type: Article
Language: Russian


Citation: A. M. Razhev, I. A. Iskakov, D. S. Churkin, A. M. Orishich, N. A. Maslov, E. O. Tsibul'skaya, A. A. Lomzov, O. V. Ermakova, A. N. Trunov, V. V. Chernykh, “Effect of laser UV radiation on the eye scleral tissue in patients with open-angle glaucoma”, Kvantovaya Elektronika, 48:5 (2018), 481–486 [Quantum Electron., 48:5 (2018), 481–486]
Linking options:
  • https://www.mathnet.ru/eng/qe16811
  • https://www.mathnet.ru/eng/qe/v48/i5/p481
  • This publication is cited in the following 4 articles:
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
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