Study of contrasting properties of nanoparticles for optical diffuse spectroscopy problems

The results of experimental studies of the optical properties of gold and silicon nanoparticle suspensions and their use as contrasting agents in optical diffusion spectroscopy (ODS) are presented. The optical properties of nanoparticle suspensions and model media were reconstructed based on the data of spectrophotometry measurements in the range 500 – 1100 nm using an original theoretical model. The experimental studies using the ODS system were performed in a liquid phantom on the basis of the solution of lipofundin and Indian ink, modelling the optical properties of a real biotissue. The enhanced contrast of images, obtained using the ODS method in the experiments with the chosen suspensions of nanoparticles confirm the assumption about high potentialities of using them as contrast agents for the ODS problems.