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This article is cited in 13 scientific papers (total in 13 papers)
Biophotonics
Analytical model of diffuse reflectance spectrum of skin tissue
S. A. Lisenkoa, M. M. Kugeikoa, V. A. Firagoa, A. N. Sobchukb a Belarusian State University, Minsk
b B. I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk
Abstract:
We have derived simple analytical expressions that enable highly accurate calculation of diffusely reflected light signals of skin in the spectral range from 450 to 800 nm at a distance from the region of delivery of exciting radiation. The expressions, taking into account the dependence of the detected signals on the refractive index, transport scattering coefficient, absorption coefficient and anisotropy factor of the medium, have been obtained in the approximation of a two-layer medium model (epidermis and dermis) for the same parameters of light scattering but different absorption coefficients of layers. Numerical experiments on the retrieval of the skin biophysical parameters from the diffuse reflectance spectra simulated by the Monte Carlo method show that commercially available fibre-optic spectrophotometers with a fixed distance between the radiation source and detector can reliably determine the concentration of bilirubin, oxy- and deoxyhaemoglobin in the dermis tissues and the tissue structure parameter characterising the size of its effective scatterers. We present the examples of quantitative analysis of the experimental data, confirming the correctness of estimates of biophysical parameters of skin using the obtained analytical expressions.
Keywords:
skin, biophysical parameters, diffuse reflectance, analytical model.
Received: 20.05.2013 Revised: 13.09.2013
Citation:
S. A. Lisenko, M. M. Kugeiko, V. A. Firago, A. N. Sobchuk, “Analytical model of diffuse reflectance spectrum of skin tissue”, Kvantovaya Elektronika, 44:1 (2014), 69–75 [Quantum Electron., 44:1 (2014), 69–75]
Linking options:
https://www.mathnet.ru/eng/qe15233 https://www.mathnet.ru/eng/qe/v44/i1/p69
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