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This article is cited in 24 scientific papers (total in 24 papers)
Optical technologies in biophysics and medicine
Fractional laser microablation of skin aimed at enhancing its permeability for nanoparticles
È. A. Geninaa, L. E. Dolotova, A. N. Bashkatova, G. S. Terentyukb, G. N. Maslyakovac, E. A. Zubkinaa, V. V. Tuchina, I. V. Yaroslavskyd, G. B. Altshulerd a OBP Research-Educational Institute of Optics and Biophotonics, Saratov State University
b LLC "The First Veterinary Clinic", Saratov
c Saratov State Medical University named after V. I. Razumovsky
d Palomar Medical Technologies, Inc., Birlington, USA
Abstract:
A new method for delivering nanoparticles into the skin using the fractional laser microablation of its surface and the ultrasonic treatment is proposed. As a result of in vitro and in vivo studies, it is shown that the 290-nm laser pulses with the energy from 0.5 to 3.0 J provide the penetration of nanoparticles of titanium dioxide with the diameter ~100 nm from the skin surface to the depth, varying from 150 to 400 μm. Histological testing of the skin areas, subjected to the treatment, shows that the particles stay in the dermis at the depth up to 400 μm no less than for three weeks.
Received: 04.04.2011
Citation:
È. A. Genina, L. E. Dolotov, A. N. Bashkatov, G. S. Terentyuk, G. N. Maslyakova, E. A. Zubkina, V. V. Tuchin, I. V. Yaroslavsky, G. B. Altshuler, “Fractional laser microablation of skin aimed at enhancing its permeability for nanoparticles”, Kvantovaya Elektronika, 41:5 (2011), 396–401 [Quantum Electron., 41:5 (2011), 396–401]
Linking options:
https://www.mathnet.ru/eng/qe14639 https://www.mathnet.ru/eng/qe/v41/i5/p396
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Abstract page: | 433 | Full-text PDF : | 127 | References: | 47 | First page: | 1 |
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