Interdisciplinary modelling of systemic mechanisms which control the reproduction and ageing

Interdisciplinary modeling and simulation of ageing and reproduction is presented. The paper describes a model where the individual ageing rate is proportional to the organism's oxygen consumption rate and its oxidative vulnerability. Ageing is understood as age-related decrease of the organism's ability to convert the substances got from ambient into energy. The models of oxidative stress and senescence-caused death allow constructing the general scheme simulating organism's life cycle. This scheme was used to analyze systemic mechanisms of reproduction and ageing in Drosophila and Medfly fruit flies.