Mathematical model of the brain hemolyquorodynamics in the application to the study of hydrocephalus

There are a large number of pathological conditions of the central nervous system characterized by impaired movement of intracerebral fluids. An important example is hydrocephalus, a pathology in which the brain ventricles increase, which leads to displacement and compression of brain tissue. This condition is well described in terms of clinical manifestations, but its causes and development are poorly understood. The report considers a complex mathematical model of cerebral cerebrospinal fluid and hemodynamics of a person based on a model of multiphase poroelasticity for brain matter. The displacement of the ventricular wall of the brain and the magnitude of pressure on it are studied. Based on the MRI data of real patients, the patterns of behavior of these values are determined depending on the parameters of the model in hydrocephalus.