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Pisma v Zhurnal Tekhnicheskoi Fiziki, 2019, Volume 45, Issue 18, Pages 33–36
DOI: https://doi.org/10.21883/PJTF.2019.18.48235.17910
(Mi pjtf5321)
 

Phosphorescence kinetics of singlet oxygen in HeLa cells suspension

V. P. Belika, D. M. Beltukovaa, T. N. Belyaevab, I. M. Gadzhieva, E. S. Kornilovab, I. K. Litvinovb, I. V. Semenovaa, O. S. Vasutinskiia

a Ioffe Institute, St. Petersburg
b Institute of Cytology Russian Academy of Science, St. Petersburg
Abstract: The kinetics of singlet oxygen phosphorescence in HeLa cells suspended in phosphate buffered saline (PBS) being generated under photosensitized excitation with Radachlorin photosensitizer has been observed and studied. The characteristic time of singlet oxygen generation and its lifetime in HeLa cells have been determined. The experimental data analysis demonstrated that the singlet oxygen lifetime in cells decreases as compared to that in Radachlorin solutions in PBS and in water, while the photosensitizer triplet state lifetime increases.
Keywords: singlet oxygen, photodynamic therapy, Radachlorin photosensitizer, HeLa cells.
Received: 06.06.2019
Revised: 10.06.2019
Accepted: 10.06.2019
English version:
Technical Physics Letters, 2019, Volume 45, Issue 9, Pages 936–939
DOI: https://doi.org/10.1134/S1063785019090165
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: V. P. Belik, D. M. Beltukova, T. N. Belyaeva, I. M. Gadzhiev, E. S. Kornilova, I. K. Litvinov, I. V. Semenova, O. S. Vasutinskii, “Phosphorescence kinetics of singlet oxygen in HeLa cells suspension”, Pisma v Zhurnal Tekhnicheskoi Fiziki, 45:18 (2019), 33–36; Tech. Phys. Lett., 45:9 (2019), 936–939
Citation in format AMSBIB
\Bibitem{BelBelBel19}
\by V.~P.~Belik, D.~M.~Beltukova, T.~N.~Belyaeva, I.~M.~Gadzhiev, E.~S.~Kornilova, I.~K.~Litvinov, I.~V.~Semenova, O.~S.~Vasutinskii
\paper Phosphorescence kinetics of singlet oxygen in HeLa cells suspension
\jour Pisma v Zhurnal Tekhnicheskoi Fiziki
\yr 2019
\vol 45
\issue 18
\pages 33--36
\mathnet{http://mi.mathnet.ru/pjtf5321}
\crossref{https://doi.org/10.21883/PJTF.2019.18.48235.17910}
\elib{https://elibrary.ru/item.asp?id=41175073}
\transl
\jour Tech. Phys. Lett.
\yr 2019
\vol 45
\issue 9
\pages 936--939
\crossref{https://doi.org/10.1134/S1063785019090165}
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