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Optics and Spectroscopy, 2018, Volume 125, Issue 1, Pages 101–104
DOI: https://doi.org/10.21883/OS.2018.07.46274.48-18
(Mi os963)
 

This article is cited in 3 scientific papers (total in 3 papers)

Nanophotonics

Nanosized particles of tantalum, hafnium, and cerium oxides used with monochromatic photon beams and brachytherapy sources

V. N. Morozovab, A. V. Belousova, G. A. Krusanovc, M. A. Kolyvanovab, P. V. Krivoshapkind, V. V. Vinogradovd, A. P. Chernyaevac, A. A. Shtilde

a Department of Physics, Moscow State University, Moscow, 119991, Russia
b Burnazyan Federal Medical Biophysical Center, Moscow, 123098, Russia
c Skobeltsyn Institute of Nuclear Physics, Moscow State University, Moscow, 119991, Russia
d ITMO University, St. Petersburg, 197101, Russia
e Blokhin Cancer Research Center, Moscow, 115478, Russia
Full-text PDF (97 kB) Citations (3)
Abstract: High-$Z$ nanoparticles can increase the absorbed radiation dose if they are accumulated in tumor cells. The quantitative measure of this radiosensitization effect is the dose enhancement factor (DEF), that is, the ratio of the doses absorbed in the presence and in the absence of nanoparticles. In the present work, the values of the dose enhancement factors of Ta$_{2}$O$_{5}$, HfO$_{2}$, and CeO$_{2}$ ceramic nanoparticles were calculated analytically for monochromatic radiation of the X-ray energy range (1–180 keV) and for low-energy sources for brachytherapy: $^{103}$Pd (mean energy, 20.6 keV), $^{125}$I (26.7 keV), and $^{131}$Cs (30.4 keV). For all types of nanoparticles in the concentration of 5 mg/mL, the values of the dose enhancement factor were high both for monochromatic radiation and for brachytherapy sources. The highest DEF values of $\sim$ 1.7 were obtained for nanoparticles of tantalum oxide. For brachytherapy sources, the highest dose enhancement factors (1.48 to 1.67) were obtained for Ta$_2$O$_5$ and HfO$_2$ nanoparticles. These results confirm that ceramic nanoparticles are promising dose modifying agents for radiotherapy.
Received: 15.02.2018
English version:
Optics and Spectroscopy, 2018, Volume 125, Issue 1, Pages 104–106
DOI: https://doi.org/10.1134/S0030400X18070196
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: V. N. Morozov, A. V. Belousov, G. A. Krusanov, M. A. Kolyvanova, P. V. Krivoshapkin, V. V. Vinogradov, A. P. Chernyaev, A. A. Shtil, “Nanosized particles of tantalum, hafnium, and cerium oxides used with monochromatic photon beams and brachytherapy sources”, Optics and Spectroscopy, 125:1 (2018), 101–104; Optics and Spectroscopy, 125:1 (2018), 104–106
Citation in format AMSBIB
\Bibitem{MorBelKru18}
\by V.~N.~Morozov, A.~V.~Belousov, G.~A.~Krusanov, M.~A.~Kolyvanova, P.~V.~Krivoshapkin, V.~V.~Vinogradov, A.~P.~Chernyaev, A.~A.~Shtil
\paper Nanosized particles of tantalum, hafnium, and cerium oxides used with monochromatic photon beams and brachytherapy sources
\jour Optics and Spectroscopy
\yr 2018
\vol 125
\issue 1
\pages 101--104
\mathnet{http://mi.mathnet.ru/os963}
\crossref{https://doi.org/10.21883/OS.2018.07.46274.48-18}
\elib{https://elibrary.ru/item.asp?id=35270046}
\transl
\jour Optics and Spectroscopy
\yr 2018
\vol 125
\issue 1
\pages 104--106
\crossref{https://doi.org/10.1134/S0030400X18070196}
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  • This publication is cited in the following 3 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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