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Optics and Spectroscopy, 2018, Volume 125, Issue 5, Page 655
DOI: https://doi.org/10.21883/OS.2018.11.46828.209-18 (Mi os852) 		 
This article is cited in 1 scientific paper (total in 1 paper)

Nanophotonics International Conference ''PCNSPA 2018 -- Photonic Colloidal Nanostructures: Synthesis, Properties, and Applications'', Saint Petersburg, Russia, June 4--8, 2018

Advanced nanotools for imaging of solid tumors and circulating and disseminated cancer cells

A. Sukhanovaab, F. Ramos-Gomesc, F. Alvescd, P. Chamesef, D. Batyef, I. Nabievab

a Laboratory of Nano-Bioengineering, National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 115409 Moscow, Russia
b Laboratoire de Recherche en Nanosciences, LRN-EA4682, Université de Reims Champagne–Ardenne, 51100 Reims, France
c Translational Molecular Imaging Unit, Max Planck Institute for Experimental Medicine, 37075 Göttingen, Germany
d Clinic of Haematology and Medical Oncology, University Medical Center Göttingen, Georg-August-Universität, 37075 Göttingen, Germany
e Aix-Marseille Université, 13009 Marseille, France
f Centre de Recherche en Cancérologie de Marseille, 13009 Marseille, France
Full-text PDF (42 kB) Citations (1)
DOI: https://doi.org/10.21883/OS.2018.11.46828.209-18
Abstract: Semiconductor quantum dots (QDs) are characterized by orders of magnitude higher multiphoton linear absorption cross-sections compared with conventional organic dyes. Combined with the QD photoluminescence quantum yield approaching 100% and their rock-solid photostability, this fact opens great prospects for the two-photon functional tumor imaging with QDs tagged with highly specific recognition molecules. Single-domain antibodies (sdAbs) or “nanobodies” derived from lamas are the smallest high-affinity recognition molecules, which may be tagged with the QDs thus permitting not only solid tumors multiphoton imaging but also rare disseminated cancer cells and micrometastases in the depth of the tissue to be detected.
Funding agency Grant number
Russian Science Foundation 17-15-01533
The Russian Science Foundation supported this study through the contract no. 17-15-01533.
Received: 06.07.2018
English version:
Optics and Spectroscopy, 2018, Volume 125, Issue 5, Pages 703–707
DOI: https://doi.org/10.1134/S0030400X18110309
Bibliographic databases:
Document Type: Article
Language: English
Citation: A. Sukhanova, F. Ramos-Gomes, F. Alves, P. Chames, D. Baty, I. Nabiev, “Advanced nanotools for imaging of solid tumors and circulating and disseminated cancer cells”, Optics and Spectroscopy, 125:5 (2018), 655; Optics and Spectroscopy, 125:5 (2018), 703–707
Citation in format AMSBIB
\Bibitem{SukRamAlv18}
\by A.~Sukhanova, F.~Ramos-Gomes, F.~Alves, P.~Chames, D.~Baty, I.~Nabiev
\paper Advanced nanotools for imaging of solid tumors and circulating and disseminated cancer cells
\jour Optics and Spectroscopy
\yr 2018
\vol 125
\issue 5
\pages 655
\mathnet{http://mi.mathnet.ru/os852}
\crossref{https://doi.org/10.21883/OS.2018.11.46828.209-18}
\elib{https://elibrary.ru/item.asp?id=36905283}
\transl
\jour Optics and Spectroscopy
\yr 2018
\vol 125
\issue 5
\pages 703--707
\crossref{https://doi.org/10.1134/S0030400X18110309}
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