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Optics and Spectroscopy, 2019, Volume 126, Issue 5, Pages 604–610
DOI: https://doi.org/10.21883/OS.2019.05.47659.8-19 (Mi os715) 		 
This article is cited in 3 scientific papers (total in 3 papers)

The 22nd Annual Conference Saratov Fall Meeting 2018 (SFM'18): VI International Symposium ''Optics and Biophotonics'' and XXII International School for Junior Scientists and Students on Optics, Laser Physics & Biophotonics
Biophotonics

Use of terahertz spectroscopy for in vivo studies of lymphedema development dynamics

Yu. V. Kistenevab, V. V. Nikolaevac, O. S. Kurochkinad, A. V. Borisovab, E. A. Sandykovaab, N. A. Krivovaa, D. K. Tuchinaae, P. A. Timoshinaae

a Tomsk State University
b Siberian State Medical University, Tomsk, Russia
c Institute of Strength Physics and Materials Science, Siberian Branch of the Russian Academy of Sciences, Tomsk, Russia
d Microsurgery Research Institute, Tomsk
e Saratov State University
Citations (3)
DOI: https://doi.org/10.21883/OS.2019.05.47659.8-19
Abstract: A laboratory model of lymphedema development induced by lymphatic vessel resection in rat extremities is presented. In vivo analysis of lymphedema development (monitoring for 4 weeks) employed reflective terahertz spectroscopy with a Dove prism. The incidence angle for an $s$-polarized electromagnetic wave directed to the boundary of the prism and the biological tissue was close to the Brewster's angle. Significant changes in the spectral characteristics of the tissue in the animals' extremities were detected on days 21–28 of lymphedema development. A predictive model for disease diagnostics based on monitoring the changes of the tissue absorbance curve in the 0.4–1.1 THz range was constructed. Principal component analysis and support vector machines were used in the model.
Funding agency Grant number
Program of fundamental scientific research of the State Academies of Sciences III.23
Russian Foundation for Basic Research 18-42-703012
The present study was performed within the framework of the Basic Research Program for State Academies of Sciences for 2013–2020, direction III.23. Financial support for the study was provided by the Russian Foundation for Basic Research and Government of Tomsk oblast within the framework of research project no. 18-42-703012.
Received: 05.12.2018
Revised: 25.12.2018
Accepted: 31.01.2019
English version:
Optics and Spectroscopy, 2019, Volume 126, Issue 5, Pages 523–529
DOI: https://doi.org/10.1134/S0030400X19050138
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: Yu. V. Kistenev, V. V. Nikolaev, O. S. Kurochkina, A. V. Borisov, E. A. Sandykova, N. A. Krivova, D. K. Tuchina, P. A. Timoshina, “Use of terahertz spectroscopy for in vivo studies of lymphedema development dynamics”, Optics and Spectroscopy, 126:5 (2019), 604–610; Optics and Spectroscopy, 126:5 (2019), 523–529
Citation in format AMSBIB
\Bibitem{KisNikKur19}
\by Yu.~V.~Kistenev, V.~V.~Nikolaev, O.~S.~Kurochkina, A.~V.~Borisov, E.~A.~Sandykova, N.~A.~Krivova, D.~K.~Tuchina, P.~A.~Timoshina
\paper Use of terahertz spectroscopy for in vivo studies of lymphedema development dynamics
\jour Optics and Spectroscopy
\yr 2019
\vol 126
\issue 5
\pages 604--610
\mathnet{http://mi.mathnet.ru/os715}
\crossref{https://doi.org/10.21883/OS.2019.05.47659.8-19}
\elib{https://elibrary.ru/item.asp?id=39133868}
\transl
\jour Optics and Spectroscopy
\yr 2019
\vol 126
\issue 5
\pages 523--529
\crossref{https://doi.org/10.1134/S0030400X19050138}
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