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This article is cited in 2 scientific papers (total in 2 papers)
Applied optics
Spectrophotometric characteristics of immunoglobulin conjugates for diagnostics of the agents of particularly dangerous infections
A. N. Spitsyna, D. V. Utkina, M. N. Kireeva, M. V. Ovchinnikovaa, O. S. Kuznetsova, P. S. Erokhina, V. I. Kochubeybc a Mikrob Russian Antiplague Research Institute, Saratov, Russia
b Saratov State University
c Tomsk State University
Abstract:
The possibility of using spectrophotometric analysis to characterize fluorescent immunoglobulins as a control method was considered. A comparative analysis of the optical properties of fluorescent immunoglobulin preparations and their constituent components - immunoglobulins, fluorochrome was carried out. The results suggest that the proposed methodological approach of optical detection of labeled immunoglobulin molecules is promising for controlling the preparation of conjugates used in the formulation of immunological reactions to identify specific antigens of pathogens of particularly dangerous infections.
Keywords:
spectrophotometry, immunoglobulins, conjugates, FITC.
Received: 25.02.2019 Revised: 16.04.2019 Accepted: 28.10.2019
Citation:
A. N. Spitsyn, D. V. Utkin, M. N. Kireev, M. V. Ovchinnikova, O. S. Kuznetsov, P. S. Erokhin, V. I. Kochubey, “Spectrophotometric characteristics of immunoglobulin conjugates for diagnostics of the agents of particularly dangerous infections”, Optics and Spectroscopy, 128:3 (2020), 430–434; Optics and Spectroscopy, 128:3 (2020), 417–421
Linking options:
https://www.mathnet.ru/eng/os459 https://www.mathnet.ru/eng/os/v128/i3/p430
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