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Optics and Spectroscopy, 2020, Volume 128, Issue 7, Pages 1020–1029
DOI: https://doi.org/10.21883/OS.2020.07.49576.65-20 (Mi os381) 		 
This article is cited in 7 scientific papers (total in 7 papers)

UV, IR, and terahertz optics

Optical properties of hyperosmotic agents for immersion clearing of tissues in terahertz spectroscopy

G. R. Musinaab, A. A. Gavdushab, N. V. Chernomyrdinab, I. N. Dolganovabc, V. E. Ulitkoc, O. P. Cherkasovade, V. N. Kurlovc, G. A. Komandina, I. V. Zhivotovskiib, V. V. Tuchinefg, K. I. Zaitsevab

a Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow
b Bauman Moscow State Technical University
c Institute of Solid State Physics, Russian Academy of Sciences, Chernogolovka, Moscow region
d Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk
e Tomsk State University
f Saratov State University
g Institute of Precision Mechanics and Control, Russian Academy of Sciences, Saratov
Full-text PDF (1364 kB) Citations (7)
DOI: https://doi.org/10.21883/OS.2020.07.49576.65-20
Abstract: We measured the transmission spectra of the most common hyperosmotic agents, such as pure glycerol, propylene glycol (PG), dimethyl sulfoxide (DMSO), polyethylene glycol (PEG) with molecular weights of 200, 300, 400, and 600 Da, their aqueous solutions, and aqueous solutions of sucrose, glucose, fructose, and dextran 40 and 70. The experiments were carried out using a THz pulsed spectrometer with an evacuated measuring compartment to eliminate the effect of water vapor on spectral measurements. We reconstructed the dielectric characteristics of hyperosmotic agents in the spectral range from 0.1 to 2.5 THz and plotted a dependence of the amplitude absorption coefficient on the concentration of the considered agents at a frequency of 0.5 THz. The results are useful for selecting optimal agents for immersion optical clearing in the THz range.
Keywords: terahertz technologies, terahertz pulsed spectroscopy, dielectric spectroscopy, immersion optical clearing, clearing agents, dehydrating agents.
Funding agency Grant number
Ministry of Science and Higher Education of the Russian Federation MK-2541.2019.8
Russian Foundation for Basic Research 19-32-50075
18-52-16025 НЦНИЛ_а
I.N. Dolganova developed the cuvette; this part was supported by the Grant of the President of the Russian Federation for the State Support of Young Russian Scientists–Candidates of Science (project no. MK-2541.2019.8). N.V. Chernomyrdin and V.V. Tuchin analyzed the absorption data for the solutions of agents with different concentrations, supported by the Russian Foundation for Basic Research (project no. 19-32-50075). V.V. Tuchin selected clearing agents with the support of the Russian Foundation for Basic Research (project no. 18-52-16025 NTsNIL_a).
Received: 18.02.2020
Revised: 03.03.2020
Accepted: 28.03.2020
English version:
Optics and Spectroscopy, 2020, Volume 128, Issue 7, Pages 1026–1035
DOI: https://doi.org/10.1134/S0030400X20070279
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: G. R. Musina, A. A. Gavdush, N. V. Chernomyrdin, I. N. Dolganova, V. E. Ulitko, O. P. Cherkasova, V. N. Kurlov, G. A. Komandin, I. V. Zhivotovskii, V. V. Tuchin, K. I. Zaitsev, “Optical properties of hyperosmotic agents for immersion clearing of tissues in terahertz spectroscopy”, Optics and Spectroscopy, 128:7 (2020), 1020–1029; Optics and Spectroscopy, 128:7 (2020), 1026–1035
Citation in format AMSBIB
\Bibitem{MusGavChe20}
\by G.~R.~Musina, A.~A.~Gavdush, N.~V.~Chernomyrdin, I.~N.~Dolganova, V.~E.~Ulitko, O.~P.~Cherkasova, V.~N.~Kurlov, G.~A.~Komandin, I.~V.~Zhivotovskii, V.~V.~Tuchin, K.~I.~Zaitsev
\paper Optical properties of hyperosmotic agents for immersion clearing of tissues in terahertz spectroscopy
\jour Optics and Spectroscopy
\yr 2020
\vol 128
\issue 7
\pages 1020--1029
\mathnet{http://mi.mathnet.ru/os381}
\crossref{https://doi.org/10.21883/OS.2020.07.49576.65-20}
\elib{https://elibrary.ru/item.asp?id=43870297}
\transl
\jour Optics and Spectroscopy
\yr 2020
\vol 128
\issue 7
\pages 1026--1035
\crossref{https://doi.org/10.1134/S0030400X20070279}
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