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CHEMISTRY AND MATERIAL SCIENCE
A plasmonic turn-on insulin sensing platform on centimeter scale nanostructure arrays
Thanh Thi Van Nguyen School of Materials Science and Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam
Abstract:
We present a plasmonic turn-on biosensing assay for insulin detection via aptamer DNA based on the plasmonic interaction of centimeter scale gold/silver double-layer nanodisk arrays and gold nanoparticles. The large-scale nanostructures were fabricated by laser interference lithography technique. The detecting optical signal-extinction spectra of the system were monitored by UV-visible spectrophotometry. The 3D finitedifference time-domain simulation was used to observe the plasmonic interaction of the sensing system. The platform exhibits an exceptionally large turn-on signal by a 120 nm red shift of the localized surface plasmonic resonance peak, results in the limit detection of 140 pM. The centimeter-scale localized surface plasmon resonance nanostructures combined with turn-on design scheme would offer a promising sensor-on-chip biosensing platform.
Keywords:
insulin sensing, localized surface plasmon, plasmonic interaction, nanostructure.
Received: 27.11.2023 Revised: 06.03.2024 Accepted: 10.03.2024
Citation:
Thanh Thi Van Nguyen, “A plasmonic turn-on insulin sensing platform on centimeter scale nanostructure arrays”, Nanosystems: Physics, Chemistry, Mathematics, 15:2 (2024), 300–306
Linking options:
https://www.mathnet.ru/eng/nano1272 https://www.mathnet.ru/eng/nano/v15/i2/p300
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Statistics & downloads: |
Abstract page: | 22 | Full-text PDF : | 18 |
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