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This article is cited in 2 scientific papers (total in 2 papers)
CHEMISTRY AND MATERIAL SCIENCE
Bioavailability of nanoemulsions modified with curcumin and cerium dioxide nanoparticles
Anastasiya D. Shirokikha, Viktoriia A. Anikinab, Elizaveta A. Zamyatinab, Ekaterina V. Mishchenkoa, Marina Yu. Korolevaa, Vladimir K. Ivanovc, Nelli R. Popovab a Mendeleev University of Chemical Technology, Moscow, Russia
b Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Russia
c Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia
Abstract:
In this work, the physicochemical properties and biological activity of nanoemulsions prepared from paraffin oil and stabilized by nonionic surfactants as carriers of curcumin and cerium dioxide nanoparticles were studied. An analysis of the results showed that curcumin was incorporated into the oil droplets while cerium dioxide nanoparticles were adsorbed on the surface of oil droplets. The nanoemulsion droplet size did not exceed 100 nm. The absence of toxicity to mouse embryonic fibroblasts in vitro and after a single intraperitoneal injection to mice in vivo makes the nanoemulsions promising drug carriers for advanced biomedical applications.
Keywords:
nanoemulsions, drug delivery, curcumin, cerium dioxide nanoparticles.
Received: 23.11.2022 Accepted: 12.12.2022
Citation:
Anastasiya D. Shirokikh, Viktoriia A. Anikina, Elizaveta A. Zamyatina, Ekaterina V. Mishchenko, Marina Yu. Koroleva, Vladimir K. Ivanov, Nelli R. Popova, “Bioavailability of nanoemulsions modified with curcumin and cerium dioxide nanoparticles”, Nanosystems: Physics, Chemistry, Mathematics, 14:1 (2023), 89–97
Linking options:
https://www.mathnet.ru/eng/nano1166 https://www.mathnet.ru/eng/nano/v14/i1/p89
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