Abstract:
New thermally stable long-chained 2-alkylisothiuronium 7-chloro-4,6-dinitrobenzofuroxan-5-olates were obtained from the corresponding bromides and 5,7-dichloro-4,6-dinitrobenzofuroxan, the hydrolysis of the C(5)–Cl bond to produce phenolic function having occurred in the course of the process. The compound structure was determined by IR spectroscopy, elemental analysis and X-ray single crystal study. Salts with C14–C18 alkyl groups revealed moderate antibacterial and antifungal activities.
Citation:
I. V. Galkina, D. I. Bakhtiyarov, L. M. Usupova, A. V. Gerasimov, M. P. Shulaeva, O. K. Pozdeev, A. V. Ilyasov, D. R. Islamov, K. S. Usachev, Yu. V. Bakhtiyarova, V. I. Galkin, “Antimicrobial activity of novel isothiuronium salts with 7-chloro-4,6-dinitrobenzofuroxan-5-olate anion”, Mendeleev Commun., 31:3 (2021), 365–367
Linking options:
https://www.mathnet.ru/eng/mendc931
https://www.mathnet.ru/eng/mendc/v31/i3/p365
This publication is cited in the following 2 articles:
E. A. Romanova, L. A. Vasileva, G. A. Gaynanova, D. I. Bakhtiyarov, I. V. Galkina, L. Ya. Zakharova, “Influence of Alkylisothiuronium Bromides and 7-Chloro-4,6-dinitrobenzofuroxan-5-olates on Liposome Key Properties”, Russ J Gen Chem, 94:10 (2024), 2797
N. A. Lozinskaya, A. A. Morozov, D. R. Bazanov, E. R. Milaeva, D. A. Areshidze, P. N. Shevtsov, L. N. Petrova, E. F. Shevtsova, “Thiouronium Salt Derivatives Based on Vicinal Diamines as Potential Neuroprotectors”, Bezopasnost' i risk farmakoterapii, 11:2 (2023), 165