Abstract:
Reaction between 2-piperidinochromane and (hetero)aromatic amines in the presence of pyridinium tosylate affords the products of replacement of the piperidine fragment by the (hetero)arylamino moiety in good yields. This single-stage process opens facile and efficient way to the functionalized N-arylchroman-2-amines.
Citation:
K. S. Korzhenko, V. A. Osyanin, D. V. Osipov, Yu. N. Klimochkin, “Transamination of 2-piperidinochromanes with (het)arylamines as a convenient route to 2-(het)arylaminochromanes”, Mendeleev Commun., 31:2 (2021), 265–267
Linking options:
https://www.mathnet.ru/eng/mendc901
https://www.mathnet.ru/eng/mendc/v31/i2/p265
This publication is cited in the following 3 articles:
Kirill S. Korzhenko, Anastasiya S. Yushkova, Darya A. Rashchepkina, Oleg P. Demidov, Dmitry V. Osipov, Vitaly A. Osyanin, “A [4+2] cycloaddition of push-pull styrenes to 1,2-naphthoquinone 1-methides: a synthesis of 2-aryl-2,3-dihydro-1H-benzo[f]chromenes”, Chem Heterocycl Comp, 59:11-12 (2023), 745
Yingwei Wang, Mingrong Yang, Chichou Lao, Zhihong Jiang, “C–H bond cleavage-enabled aerobic ring-opening reaction of in situ formed 2-aminobenzofuran-3(2H)-ones”, Org. Biomol. Chem., 19:43 (2021), 9448
V. A. Osyanin, I. A. Semenova, A. G. Groshev, D. V. Osipov, Yu. N. Klimochkin, “A cascade formation of N-pyridylacrylamides from pyrido[1,2-a]pyrimidine diones and chromene aldehydes”, Mendeleev Commun., 31:6 (2021), 859–861
Contact us: