Abstract:
The reaction of methyl a-bromoisobutyrate or 1-bromocycloalkanecarboxylates with zinc and 2,5-diphenyl-1,3,4-oxadiazole leads to 5-phenyl-2,4-dihydro-3H-pyrazol-3-one derivatives, with the cycloalkane series affording products of spiro structure. In the case of cyclobutane reactant, 3-phenyl-2,4,5,6-tetrahydropyrano[2,3-c]pyrazole is also formed.
Citation:
E. A. Nikiforova, N. F. Kirillov, D. V. Baibarodskikh, S. N. Shurov, M. V. Dmitriev, D. P. Zverev, “Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole”, Mendeleev Commun., 31:2 (2021), 248–250
Linking options:
https://www.mathnet.ru/eng/mendc895
https://www.mathnet.ru/eng/mendc/v31/i2/p248
This publication is cited in the following 1 articles:
Yaroslav K. Gorbunov, Leonid L. Fershtat, Advances in Heterocyclic Chemistry, 143, 2024, 1