Abstract:
Using a mouse model, an organ distribution for microgels of carboxymethyl cellulose cross-linked with 67Cu2+ ions was investigated and compared with the distribution of free 67Cu2+ ions from 67CuCl2. The clearance of the microgels through both liver and kidneys was demonstrated. An additional examination of distribution for [3H]CMC microparticles and [3H]CMC–Cu microgels revealed no copper release from the microgels in vivo.
Citation:
M. A. Orlova, V. V. Spiridonov, G. A. Badun, T. P. Trofimova, A. P. Orlov, A. S. Zolotova, A. B. Priselkova, G. Yu. Aleshin, M. G. Chernysheva, A. A. Yaroslavov, S. N. Kalmykov, “In vivo behavior of carboxymethylcellulose based microgels containing 67Cu”, Mendeleev Commun., 32:5 (2022), 658–660
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https://www.mathnet.ru/eng/mendc758
https://www.mathnet.ru/eng/mendc/v32/i5/p658
This publication is cited in the following 6 articles:
G. A. Badun, M. G. Chernysheva, “Tritium Thermal Activation Method. Features of Application, Modern Achievements, and Further Development Prospects”, Radiochemistry, 65:2 (2023), 185
G. A Badun, M. G Chernysheva, “Metod termicheskoy aktivatsii tritiya. osobennosti primeneniya, sovremennye dostizheniya i dal'neyshie perspektivy razvitiya”, Radiohimiâ, 65:2 (2023), 158
O. V. Surov, M. I. Voronova, “An approach to enhanced redispersibility of cellulose nanocrystals via freeze-drying their Pickering emulsions”, Mendeleev Commun., 33:2 (2023), 272–274
L. V. Sigolaeva, O. V. Efremova, D. V. Pergushov, “Temperature behavior of glucose oxidase immobilized into surface-attached stimuli-sensitive copolymer microgel”, Mendeleev Commun., 33:4 (2023), 559–561
A. V. Sarantsev, G. S. Mikhaylov, A. V. Gopin, G. A. Badun, M. G. Chernysheva, A. L. Nikolaev, “The effect of tritiated water on the alkaline phosphatase inactivation after ultrasound and gamma-rays irradiation”, Mendeleev Commun., 33:6 (2023), 858–860
M. A. Orlova, T. P. Trofimova, A. S. Zolotova, A. A. Larenkov, A. P. Orlov, A. A. Borodkov, V. V. Spiridonov, “Radiation stability of carboxymethylcellulose microgels cross-linked by copper ions”, Russ Chem Bull, 71:11 (2022), 2515