aSchool of Chemical and Pharmaceutical Engineering, Changzhou Vocational Institute of Engineering, Changzhou, P.R. China bSchool of Petrochemical Engineering, Changzhou University, Changzhou, China
Abstract:
An efficient and green protocol for the A3 coupling reaction of aldehyde, amine and alkyne involves the use of copper nanoparticles and β-cyclodextrin in water. The copper nanoparticles are generated in situ by reduction with green and cheap sodium hydroxymethanesulfinate (rongalite) while β-cyclodextrin serves as a stabilizing agent and a phase-transfer catalyst.
Citation:
Ya.-J. Fan, D. Wang, L. Wang, Y. Zhou, “Synthesis of propargylamines catalyzed by in situ generated copper nanoparticles in water”, Mendeleev Commun., 33:6 (2023), 829–831
Linking options:
https://www.mathnet.ru/eng/mendc539
https://www.mathnet.ru/eng/mendc/v33/i6/p829
This publication is cited in the following 2 articles:
Y. Zhou, Ya.-J. Fan, L. Wang, “β-Cyclodextrin-stabilized Cu nanoparticles catalyzed C–O coupling to access 2-aryloxypyridines”, Mendeleev Commun., 34:2 (2024), 270–271
Y. Zhang, J. Bai, S. Sun, “Copper(ii)-catalyzed three-component coupling sequence for the efficient synthesis of 2-arylquinolines: 1,4-dioxane serving as the C2 building block”, Mendeleev Commun., 34:3 (2024), 401–403
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