Abstract:
A synthetic route to 1,4-benzothiazine-2-carboxylic acid 1,1 -dioxides, analogues of the ‘fluoroquinolone’ family of antibacterials, has been developed; unfortunately, the target compound (the thia-analogue of pefloxacin) has not revealed remarkable antibacterial activity in vitro against the majority of the strains tested.
Document Type:
Article
Language: English
Citation:
V. I. Vysokov, V. N. Charushin, G. B. Afanasyeva, O. N. Chupakhin, “The Synthesis of Fluorinated 4H-1,4-Benzothiazine-2-carboxylic Acid 1,1-Dioxides—Thionated Analogues of Pefloxacin”, Mendeleev Commun., 3:4 (1993), 159–160
Linking options:
https://www.mathnet.ru/eng/mendc5310
https://www.mathnet.ru/eng/mendc/v3/i4/p159
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