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Mendeleev Communications, 1993, Volume 3, Issue 4, Pages 159–160
DOI: https://doi.org/10.1070/MC1993v003n04ABEH000267
(Mi mendc5310)
 

This article is cited in 8 scientific papers (total in 8 papers)

The Synthesis of Fluorinated 4H-1,4-Benzothiazine-2-carboxylic Acid 1,1-Dioxides—Thionated Analogues of Pefloxacin

V. I. Vysokova, V. N. Charushinb, G. B. Afanasyevaa, O. N. Chupakhinc

a Department of Technology of Organic Synthesis, Urals State Technical University, Ekaterinburg, Russian Federation
b Department of Organic Chemistry, Urals State Technical University, Ekaterinburg, Russian Federation
c I. Ya. Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
Full-text PDF (337 kB) Citations (8)
Abstract: A synthetic route to 1,4-benzothiazine-2-carboxylic acid 1,1 -dioxides, analogues of the ‘fluoroquinolone’ family of antibacterials, has been developed; unfortunately, the target compound (the thia-analogue of pefloxacin) has not revealed remarkable antibacterial activity in vitro against the majority of the strains tested.
Document Type: Article
Language: English


Citation: V. I. Vysokov, V. N. Charushin, G. B. Afanasyeva, O. N. Chupakhin, “The Synthesis of Fluorinated 4H-1,4-Benzothiazine-2-carboxylic Acid 1,1-Dioxides—Thionated Analogues of Pefloxacin”, Mendeleev Commun., 3:4 (1993), 159–160
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  • This publication is cited in the following 8 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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