Abstract:
Intramolecular cyclization of α-cyano-β-(3-p-nitrophenylaminoindol-2-yl)acrylonitrile yields 1-p-nitrophenyl-2-imino-3-cyano-1,2-dihydropyrido[3,2-b]indole 7, methylation of which by methyl iodide in acetone in the presence of potassium carbonate is accompanied by the addition of acetonyl anion and formation of 1-p-nitrophenyl-2-dimethylamino-3-cyano-4-acetonyl-1,4-dihydropyrido[3,2-b]indole 9.
Document Type:
Article
Language: English
Citation:
S. Yu. Ryabova, L. M. Alekseeva, V. G. Granik, “A New Approach to the Synthesis of 1,2- and 1,4-Dihydropyrido[3,2-b]indole Derivatives”, Mendeleev Commun., 5:3 (1995), 107–109
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https://www.mathnet.ru/eng/mendc5054
https://www.mathnet.ru/eng/mendc/v5/i3/p107
This publication is cited in the following 8 articles:
S. Yu. Ryabova, L. M. Alekseeva, V. G. Granik, “Reduction of 2-amino-1-(4-nitrophenyl)-1 H-pyrido[3,2-b]indole-3-carbonitrile by sodium borohydride and sodium cyanoborohydride”, Russ Chem Bull, 58:3 (2009), 634
S. Yu. Ryabova, L. M. Alekseeva, B. G. Granik, “1H-pyrido[3,2-b]indoles. Synthesis and investigation of some their spectroscopic and chemical properties”, Chem Heterocycl Compd, 36:3 (2000), 301
Vladimir G. Granik, Vadim A. Makarov, Cyril Párkányi, Advances in Heterocyclic Chemistry, 72, Advances in Heterocyclic Chemistry Volume 72, 1998, 283
S. Yu. Ryabova, L. M. Alekseeva, V. G. Granik, “2-formyl-3-arylaminoindoles in the synthesis of 1,2- and 1,4-dihydro-5H-pyrido[3,2-b]indole (δ-carboline) derivatives”, Pharm Chem J, 30:9 (1996), 579
S. Yu. Ryabova, N. Z. Tugusheva, L. M. Alekseeva, V. G. Granik, “3-arylaminoindoles in the synthesis of indolo[3,2-b]quinoline derivatives”, Pharm Chem J, 30:7 (1996), 472
S. Yu. Ryabova, Yu. I. Trofimkin, L. M. Alekseeva, I. F. Kerbnikova, G. Ya. Shvarts, V. G. Granik, “Synthesis and biological activity of dienediaminoketones of the indolin-3-one and 2-pyrrolin-4-one series”, Pharm Chem J, 29:9 (1995), 610
S. YU. RYABOVA, L. M. ALEKSEEVA, V. G. GRANIK, “ChemInform Abstract: New Approach to the Synthesis of 1,2‐ and 1,4‐Dihydropyrido(3,2‐b) indole Derivatives.”, ChemInform, 26:38 (1995)
S. Yu. Ryabova, V. G. Granik, “Advances in indoxyl chemistry (review)”, Pharm Chem J, 29:12 (1995), 809
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