Abstract:
The efficient Lewis acid assisted cyclisation of β-phenylethylamide into dihydroisoquinolines was optimised in relation to metal chloride catalyst, and by X-ray crystallography a new type of non-bonded interaction in the cyclic systems was demonstrated: face coordination of the Cl-anion and an electron deficient pyridinium π-system.
Document Type:
Article
Language: English
Citation:
E. A. Mistryukov, O. N. Sorokina, A. E. Mistryukov, “Lewis acid mediated cyclisation of β-phenylethylamides with an unactivated benzene ring: an efficient preparation of dihydroisoquinolines”, Mendeleev Commun., 6:6 (1996), 39–241
Linking options:
https://www.mathnet.ru/eng/mendc4983
https://www.mathnet.ru/eng/mendc/v6/i6/p39
This publication is cited in the following 3 articles:
Mengdie Tang, Man Wang, Songyang Li, Chenxi Guo, Ran Song, Daoshan Yang, Jian Lv, “Switchable Chemoselectivity in [3 + 3] Annulation of β,γ-Unsaturated α-Ketoesters and 1H-Pyrazol-5-amines by Cooperative Acid Catalysis with NiII and InI”, Org. Lett., 26:32 (2024), 6894
Mengwei Li, Yuan Yuan, Yulan Chen, “Bischler‐Napieralski Cyclization: A Versatile Reaction towards Functional Aza‐PAHs and Their Conjugated Polymers†”, Chin. J. Chem., 39:11 (2021), 3101
E. A. MISTRYUKOV, O. N. SOROKINA, A. E. MISTRYUKOV, “ChemInform Abstract: Lewis Acid Mediated Cyclization of β‐Phenylethylamides with an Unactivated Benzene Ring: An Efficient Preparation of Dihydroisoquinolines.”, ChemInform, 28:15 (1997)
Contact us: