Abstract:
A mathematical model has been constructed for the anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines based on a systematic search of such sets of pairs of fragments, whose presence or absence in the molecules studied considerably affects their biological activity.
Document Type:
Article
Language: English
Citation:
G. M. Makeev, M. Kumskov, “The relationship between the structure and anti-AIDS activity of polyhydroxypiperidines and polyhydroxypyrrolidines”, Mendeleev Commun., 6:1 (1996), 27–29
Linking options:
https://www.mathnet.ru/eng/mendc4898
https://www.mathnet.ru/eng/mendc/v6/i1/p27
This publication is cited in the following 4 articles:
Camilla Matassini, Stefania Mirabella, Xhenti Ferhati, Cristina Faggi, Inmaculada Robina, Andrea Goti, Elena Moreno‐Clavijo, Antonio J. Moreno‐Vargas, Francesca Cardona, “Polyhydroxyamino‐Piperidine‐Type Iminosugars and Pipecolic Acid Analogues from a D‐Mannose‐Derived Aldehyde”, Eur J Org Chem, 2014:25 (2014), 5419
Birgitte M. Malle, Inge Lundt, Tanja M. Wrodnigg, “Regioselective intramolecular ring closure of 2-amino-6-bromo-2,6-dideoxyhexono-1,4-lactones to 5- or 6-membered iminuronic acid analogues: synthesis of 1-deoxymannojirimycin and 2,5-dideoxy-2,5-imino-d-glucitol”, Org. Biomol. Chem., 6:10 (2008), 1779
G. M. Makeev, M. Kumskov, “Modelling of the 'structure–biological activity' relationship for conformationally mobile molecules”, Mendeleev Commun., 8:2 (1998), 62–65
G. M. MAKEEV, M. I. KUMSKOV, “ChemInform Abstract: The Relationship Between the Structure and anti‐AIDS Activity of Polyhydroxypiperidines and Polyhydroxypyrrolidines”, ChemInform, 27:25 (1996)
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