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Mendeleev Communications, 2023, Volume 33, Issue 5, Pages 624–626
DOI: https://doi.org/10.1016/j.mencom.2023.09.011 (Mi mendc476) 		 
This article is cited in 2 scientific papers (total in 2 papers)

Communications

Sortase-promoted synthesis of homooligomers from a monomeric protein

T. D. Melikhova, N. V. Bovin, A. D. Antipov, M. N. Tereshin, R. H. Ziganshin, A. B. Tuzikov

M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
Full-text PDF (334 kB) Citations (2)
DOI: https://doi.org/10.1016/j.mencom.2023.09.011
Abstract: We demonstrated covalent cross-linking of two or three protein molecules specifically at the C-terminus by sortase-catalyzed conjugation of recombinant proteins with conformationally rigid-flexible tetraantennary templates, where structure of the antenna is [Gly-Gly-(N-CH2COOH)Gly]nCH2–.
Keywords: bioconjugation, sortase, protein A, oligoglycine, protein homooligomerization.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.5 Mb)


Citation: T. D. Melikhova, N. V. Bovin, A. D. Antipov, M. N. Tereshin, R. H. Ziganshin, A. B. Tuzikov, “Sortase-promoted synthesis of homooligomers from a monomeric protein”, Mendeleev Commun., 33:5 (2023), 624–626
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  • https://www.mathnet.ru/eng/mendc476
  • https://www.mathnet.ru/eng/mendc/v33/i5/p624
    • This publication is cited in the following 2 articles:
    1. T. D. Melikhova, N. V. Bovin, N. S. Shoshina, T. V. Bobik, L. A. Gavrilov, M. A. Sablina, E. M. Rapoport, V. N. Stepanenko, A. B. Tuzikov, Mendeleev Commun., 35:2 (2025), 136–138  mathnet  crossref
    2. I. M. Ryzhov, P. S. Obukhova, O. E. Galanina, E. M. Rapoport, N. S. Egorova, N. V. Bovin, A. B. Tuzikov, “Synthesis of pseudocyclic peptide of protein S of SARS-CoV-2 and its interaction with diagnostically significant antibodies of COVID-19 patients”, Mendeleev Commun., 34:4 (2024), 499–501  mathnet  crossref
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
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