aDepartment of Chemistry and Technology, Tver State University, Tver, Russian Federation bAll-Russian Scientific Research Institute for Physical-Engineering and Radiotechnical Metrology, Mendeleevo, Moscow Region, Russian Federation cV.N. Orekhovich Institute of Biomedical Chemistry, Moscow, Russian Federation
Abstract:
Polypeptide-like supramolecular aggregates are formed in aqueous cysteine–AgNO3 solution. At low pH, their positively charged shell consists of several layers of cysteine–Ag+ complexes held by hydrogen bonds; with an increase in pH, the particles aggregate at isoelectric point; while at higher pH, the shell acquires negative charge and starts being destroyed. The pH control has been demonstrated for cytotoxic effect of the solution against MCF-7 breast cancer cells
Citation:
D. V. Vishnevetskii, E. M. Semenova, D. V. Averkin, A. R. Mekhtiev, “Behavior and bioactive properties of aqueous L-cysteine–AgNO3 solution at different pH”, Mendeleev Commun., 33:3 (2023), 431–432
Linking options:
https://www.mathnet.ru/eng/mendc419
https://www.mathnet.ru/eng/mendc/v33/i3/p431
This publication is cited in the following 4 articles: