Abstract:
The pentasaccharide Galβ1-4GlcNAcβ1-6(Galβ1-4GlcNAcβ1-3)GalNAcαOR, its partial trisaccharides Galβ1-4GlcNAcβ1- 3GalNAcαOR and Galβ1-4GlcNAcβ1-6GalNAcαOR and the tetrasaccharide Galβ1-4GlcNAcβ1-6(Galβ1-3)GalNAcαOR were synthesised as spacered derivatives (R = CH2CH2CH2NH2) using a Troc-protected lactosamine glycosyl donor at the key stage.
Document Type:
Article
Language: English
Citation:
G. V. Pazynina, V. V. Severov, N. V. Bovin, “Synthesis of N-acetyllactosamine-terminated oligosaccharides — fragments of glycoprotein O-chains”, Mendeleev Commun., 12:5 (2002), 183–184
Linking options:
https://www.mathnet.ru/eng/mendc4153
https://www.mathnet.ru/eng/mendc/v12/i5/p183
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V. V. Severov, G. V. Pazynina, T. V. Ovchinnikova, N. V. Bovin, “The synthesis of oligosaccharides containing internal and terminal Galβ1-3GlcNAcβ fragments”, Russ J Bioorg Chem, 41:2 (2015), 147
Dolores Solís, Nicolai V. Bovin, Anthony P. Davis, Jesús Jiménez-Barbero, Antonio Romero, René Roy, Karel Smetana, Hans-Joachim Gabius, “A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code”, Biochimica et Biophysica Acta (BBA) - General Subjects, 1850:1 (2015), 186
G. V. Pazynina, S. V. Tsygankova, N. V. Bovin, “Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc”, Mendeleev Commun., 25:4 (2015), 250–251
Tanja Larsen, Yayoi Yoshimura, Bjørn G.R. Voldborg, Giuseppe Cazzamali, Nicolai V. Bovin, Ulrika Westerlind, Monica M. Palcic, Jørgen J. Leisner, “Human chitotriosidase CHIT1 cross reacts with mammalian‐like substrates”, FEBS Letters, 588:5 (2014), 746
V. V. Severov, I. M. Belyanchikov, G. V. Pazynina, N. V. Bovin, “Synthesis of N-acetyllactosamine-containing oligosaccharides, galectin ligands”, Russ J Bioorg Chem, 33:1 (2007), 122
Ola Blixt, Steve Head, Tony Mondala, Christopher Scanlan, Margaret E. Huflejt, Richard Alvarez, Marian C. Bryan, Fabio Fazio, Daniel Calarese, James Stevens, Nahid Razi, David J. Stevens, John J. Skehel, Irma van Die, Dennis R. Burton, Ian A. Wilson, Richard Cummings, Nicolai Bovin, Chi-Huey Wong, James C. Paulson, “Printed covalent glycan array for ligand profiling of diverse glycan binding proteins”, Proc. Natl. Acad. Sci. U.S.A., 101:49 (2004), 17033
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