Abstract:
Multicomponent one-pot reactions of aromatic aldehydes, cyanothioacetamide, ethyl benzoylacetate, acetone and malononitrile in the presence of N-methylmorpholine or similar reactions of pyridinethiones or -thiolates with malononitrile and acetone afford the title compounds, which were unknown before.
Document Type:
Article
Language: English
Citation:
V. V. Dotsenko, S. G. Krivokolylsko, V. P. Litvinov, “Multicomponent one-pot synthesis of pyrido[3′,2′:4,5]thieno[3,2-b]pyridines as a novel approach to condensed pyridines”, Mendeleev Commun., 13:6 (2003), 267–268
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https://www.mathnet.ru/eng/mendc4057
https://www.mathnet.ru/eng/mendc/v13/i6/p267
This publication is cited in the following 13 articles:
V. V. Dotsenko, V. S. Muraviev, D. Yu. Lukina, V. D. Strelkov, N. A. Aksenov, I. V. Aksenova, G. D. Krapivin, L. V. Dyadyuchenko, “Reaction of 3-Amino-4,6-diarylthieno[2,3-b]pyridine-2-carboxamides with Ninhydrin”, Russ J Gen Chem, 90:6 (2020), 948
D. S. Buryi, V. V. Dotsenko, N. A. Aksenov, I. V. Aksenova, S. G. Krivokolysko, L. V. Dyadyuchenko, “Synthesis and Properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines”, Russ J Gen Chem, 89:8 (2019), 1575
D. S. Buryi, V. V. Dotsenko, N. A. Aksenov, I. V. Aksenova, “Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives”, Russ J Gen Chem, 89:9 (2019), 1744
E. A. Chigorina, A. V. Bespalov, V. V. Dotsenko, “Synthesis and Cyclizations of N-(Thieno[2,3-b]pyridin-3-yl)cyanoacetamides”, Russ J Gen Chem, 89:10 (2019), 2018
Tatyana A. Stroganova, Vladimir K. Vasilin, Victor V. Dotsenko, Nikolai A. Aksenov, Gennady D. Krapivin, “Reaction of thieno[2,3-b]pyridines with sodium hypochlorite: An unusual and stereoselective one-pot approach to dimeric pyrrolo[2′,3′:4,5]thieno[2,3-b]pyridines”, Tetrahedron Letters, 60:14 (2019), 997
V. V. Dotsenko, D. V. Sventukh, S. G. Krivokolysko, “Condensed sulfur-containing pyridine systems 3.* Construction of penta- and hexacyclic heterocyclic systems by the cascade reaction of 3-cyanopyridine-2(1H)-thiones and 3-cyano-pyridine-2(1H)-thiolates with 8-chloromethyl-3-methyl-7-(2-oxo-2-phenylethyl)xanthene”, Chem Heterocycl Comp, 48:9 (2012), 1397
Iryna O. Lebedyeva, Victor V. Dotsenko, Vladimir V. Turovtsev, Sergey G. Krivokolysko, V'yacheslav M. Povstyanoy, Mikhaylo V. Povstyanoy, “The Thorpe–Ziegler-type reaction of 3-cyanopyridine-2(1H)-thiones with Biginelli 6-bromomethyl-3,4-dihydropyrimidin-2(1H)-ones: cascade assembling of tetra- and pentacyclic heterocyclic scaffolds”, Tetrahedron, 68:47 (2012), 9729
V. V. Dotsenko, I. A. Lebedeva, S. G. Krivokolysko, M. V. Povstyanoi, V. M. Povstyanoi, E. O. Kostyrko, “Reaction of ethyl 4-aryl-6-bromomethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates with N-methylmorpholinium 3-cyano-1,4-dihydro- and 3-cyano-1,4,5,6-tetrahydropyridine-2-thiolates”, Chem Heterocycl Comp, 48:3 (2012), 462
V. V. Dotsenko, S. G. Krivokolysko, V. P. Litvinov, “New cascade synthesis of pyrido[2',3':4,5]thieno- [2,3-b]pyridine derivatives”, Chem Heterocycl Comp, 45:2 (2009), 253
V. N. Britsun, A. N. Esipenko, M. O. Lozinskii, “Heterocyclization of thioamides containing an active methylene group (review)”, Chem Heterocycl Comp, 44:12 (2008), 1429
V.P. Litvinov, V.V. Dotsenko, S.G. Krivokolysko, Advances in Heterocyclic Chemistry, 93, Advances in Heterocyclic Chemistry Volume 93, 2007, 117
V. P. Litvinov, V. V. Dotsenko, S. G. Krivokolysko, “Thienopyridines: synthesis, properties, and biological activity”, Russ Chem Bull, 54:4 (2005), 864
Victor V. Dotsenko, Sergey G. Krivokolysko, Victor P. Litvinov, “Multicomponent One‐Pot Synthesis of Pyrido[3′,2′:4,5]thieno[3,2‐b]pyridines as a Novel Approach to Condensed Pyridines.”, ChemInform, 35:20 (2004)
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