D. V. Beigulenko, A. S. Semyonkin, J. A. Malinovskaya, P. A. Melnikov, E. I. Medyankina, T. S. Kovshova, Yu. V. Ermolenko, S. E. Gelperina, “Internalization of PLGA nanoparticles coated with poloxamer 188 in glioma cells: A confocal laser scanning microscopy study”, Mendeleev Commun., 33:3 (2023), 340

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Mendeleev Communications, 2023, Volume 33, Issue 3, Pages 340–342
DOI: https://doi.org/10.1016/j.mencom.2023.04.014 (Mi mendc391)

This article is cited in 2 scientific papers (total in 2 papers)

Communications

Internalization of PLGA nanoparticles coated with poloxamer 188 in glioma cells: A confocal laser scanning microscopy study

D. V. Beigulenko^a, A. S. Semyonkin^a, J. A. Malinovskaya^a, P. A. Melnikov^b, E. I. Medyankina^c, T. S. Kovshova^a, Yu. V. Ermolenko^a, S. E. Gelperina^a

^a D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^b V.P. Serbsky National Medical Research Centre of Psychiatry and Narcology, Moscow, Russian Federation
^c N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation

Full-text PDF (1125 kB) Citations (2)

DOI: https://doi.org/10.1016/j.mencom.2023.04.014

Graphic abstract: Internalization of PLGA nanoparticles coated with poloxamer 188 in glioma cells: A confocal laser scanning microscopy study

Abstract: Internalization of poloxamer 188-coated PLGA nanoparticles (NPs) in GL261 murine glioma cells was studied using confocal laser scanning microscopy. For visualization, both poloxamer 188 (P188) and PLGA were labeled covalently with fluorescent dyes Rhodamine B and Cyanine5, respectively. The results indicated that the PLGA NPs coated with poloxamer 188 enter a cell as an integral core–shell structure, which can be helpful for gaining further insight into the in vivo performance of surfactant-coated polymeric NPs as core–shell delivery systems

Keywords: poloxamer 188, confocal laser scanning microscopy (CLSM), polylactide-co-glycolide nanoparticles (PLGA NPs), GL261 murine glioma cells, Rhodamine B.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(879.7 Kb)

Citation: D. V. Beigulenko, A. S. Semyonkin, J. A. Malinovskaya, P. A. Melnikov, E. I. Medyankina, T. S. Kovshova, Yu. V. Ermolenko, S. E. Gelperina, “Internalization of PLGA nanoparticles coated with poloxamer 188 in glioma cells: A confocal laser scanning microscopy study”, Mendeleev Commun., 33:3 (2023), 340–342

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https://www.mathnet.ru/eng/mendc/v33/i3/p340

This publication is cited in the following 2 articles:

Salah Alghareeb, Kofi Asare-Addo, Barbara R. Conway, Adeola O. Adebisi, “PLGA nanoparticles for nasal drug delivery”, Journal of Drug Delivery Science and Technology, 95 (2024), 105564
Tatyana Kovshova, Julia Malinovskaya, Julia Kotova, Marina Gorshkova, Lyudmila Vanchugova, Nadezhda Osipova, Pavel Melnikov, Veronika Vadekhina, Alexey Nikitin, Yulia Ermolenko, Svetlana Gelperina, “Core–Shell PLGA Nanoparticles: In Vitro Evaluation of System Integrity”, Biomolecules, 14:12 (2024), 1601

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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