Abstract:
The condensation of 3-methyl-1-phenyl-5-pyrrolidinopyrazole-4-carboxaldehyde with N,N-dimethylbarbituric acid or Meldrum's acid followed by cyclization of the Knövenagel product by in a ‘tert-amino effect’ reaction resulted in the heterocyclic spiroderivatives of pyrazolo[3,4-e]indolizine.
Document Type:
Article
Language: English
Citation:
O. S. Eltsov, E. V. D'yachenko, T. V. Glukhareva, Yu. Yu. Morzherin, “Synthesis of spirocyclic 4,5,5a,6,7,8-hexahydro-1H-pyrazolo[3,4-e]indolizine derivatives”, Mendeleev Commun., 15:3 (2005), 119–120
Linking options:
https://www.mathnet.ru/eng/mendc3703
https://www.mathnet.ru/eng/mendc/v15/i3/p119
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Subas M. Sakya, Barbara Abrams, Sheri L. Snow, Bryson Rast, “Facile microwave assisted decarbonylation of 4-formyl group in 5-alkyl amino substituted pyrazoles”, Tetrahedron Letters, 49:14 (2008), 2280
Sergey V. Ryabukhin, Andrey S. Plaskon, Dmitriy M. Volochnyuk, Sergey E. Pipko, Andrey A. Tolmachev, “Facile One-Pot Synthesis of 1,2,3,4-Tetrahydroquinoline-3-carboxylic Acids and Their Heterocyclic Analogs”, Synthetic Communications, 38:17 (2008), 3032
Oleg S. Eltsov, Elisaveta V. D'yachenko, Tatiana V. Glukhareva, Yury Yu. Morzherin, “Synthesis of Spirocyclic 4,5,5a,6,7,8‐Hexahydro‐1H‐pyrazolo[3,4‐e]indolizine Derivatives.”, ChemInform, 36:39 (2005)
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