Abstract:
The interaction of 2-(4-R-piperidino)benzaldehyde and cyclic CH-active compounds occurred as a tandem of Knövenagel condensation and cyclization by tert-amino effect and led to spiro-fused 3-substituted 2,3,4,4a,5,6-hexahydro-6H-benzo[c]quinolizine.
Document Type:
Article
Language: English
Citation:
E. V. Deeva, T. V. Glukhareva, A. V. Tkachev, Yu. Yu. Morzherin, “Stereoselective synthesis of spirofused 3-substituted 2,3,4,4a,5,6-hexahydro- 6H-benzo[c]quinolizine using the tert-amino effect”, Mendeleev Commun., 16:2 (2006), 82–83
Linking options:
https://www.mathnet.ru/eng/mendc3529
https://www.mathnet.ru/eng/mendc/v16/i2/p82
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A. Yu. Platonova, T. V. Glukhareva, O. A. Zimovets, Yu. Yu. Morzherin, “tert-Amino effect: the Meth-Cohn and Reinhoudt reactions (Review)”, Chem Heterocycl Comp, 49:3 (2013), 357
Victoria V. Lipson, Nikolay Yu. Gorobets, “One hundred years of Meldrum's acid: advances in the synthesis of pyridine and pyrimidine derivatives”, Mol Divers, 13:4 (2009), 399
T. V. Glukhareva, E. V. Deeva, A. Yu. Platonova, I. V. Geide, M. I. Kodess, Yu. Yu. Morzherin, “Diastereoselective synthesis of spiro derivatives of 3-substituted 2,3,4,4a,5,6-hexahydro-1H-benzo[c]quinolizines”, Russ J Org Chem, 45:5 (2009), 743
E. Kleinpeter, M. Sefkow, Comprehensive Heterocyclic Chemistry III, 2008, 739
T. V. Glukharev, E. P. Klimova, A. Yu. Platonova, Yu. Yu. Morzherin, “Interaction of 2-piperazinobenzaldehyde with cyanoacet(thio)amide: Stereoselective cyclization by the “tert-amino effect” mechanism”, Chem Heterocycl Comp, 44:6 (2008), 759
T. V. Glukhareva, P. E. Kropotina, M. F. Kosterina, Yu. I. Nein, E. V. Deeva, Yu. Yu. Morzherin, “Stereoselective synthesis of new spiro-fused heterocyclic systems, 2,3,4,4a,5.6-hexahydro-6H-spiro[benzo[c]quinolizine-5,4′-pyrazol]-5′-ones”, Chem Heterocycl Compd, 43:1 (2007), 76
Elisaveta V. Deeva, Tatiana V. Glukhareva, Alexey V. Tkachev, Yury Yu. Morzherin, “Stereoselective Synthesis of Spirofused 3‐Substituted 2,3,4,4a,5,6‐Hexahydro‐6H‐benzo[c]quinolizine Using the tert‐Amino Effect.”, ChemInform, 37:37 (2006)
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