Abstract:
Novel class of multicomponent quinolone antibiotics,crystalline hydrogen peroxide adducts of nalidixic acid C12H12N2O3 · H2O2 and ciprofloxacin C17H18F1N3O3 · 5 H2O2, were prepared from highly concentrated hydrogen peroxide, and their structures were determined by X-ray crystallography. The second compound contains decameric H-bonded hydrogen peroxide clusters, which makes this substance one of the richest in hydrogen peroxide among organic peroxosolvates.
Citation:
M. A. Kiseleva, P. V. Prikhodchenko, A. V. Churakov, “Novel peroxosolvates of quinolone antibiotics containing large hydrogen peroxide clusters”, Mendeleev Commun., 34:1 (2024), 25–27
Linking options:
https://www.mathnet.ru/eng/mendc33
https://www.mathnet.ru/eng/mendc/v34/i1/p25
This publication is cited in the following 4 articles:
Alexander G. Medvedev, Petr V. Prikhodchenko, Igor L. Dalinger, Mikhail V. Vener, Andrei V. Churakov, “Combined X-ray Crystallographic and Periodic DFT Study of Supramolecular Organization and Intermolecular Interactions in Crystalline Peroxosolvates of (Nitropyrazolyl)furazans”, Crystal Growth & Design, 2025
Andrei V. Churakov, “Three peroxomorphic H2O2 adducts of antibiotic furacin: the first cases of 2D hydrogen-bonded peroxide layers and concerted flip-flop hydrogen disorder of peroxide species”, CrystEngComm, 26:42 (2024), 5996
S.S. Kiselev, Yu.A. Borisov, M.I. Budnik, “Theoretical studies the structure and properties of bicyclic and tricyclic hydrogen peroxide clusters (H2O2)n, n = 8–21: MP2 and DFT calculations”, Computational and Theoretical Chemistry, 1238 (2024), 114708
S. S. Kiselev, Yu. A. Borisov, “Theoretical studies of the structure and properties of cyclic hydrogen peroxide clusters: quantum chemical calculations”, Russ Chem Bull, 73:10 (2024), 2821
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