Abstract:
A one-pot synthesis of N,N'-disubstituted (3bR*,7aR*,10bR*,14aR*)-octadecahydro-1H ,8H-2,3a,7b,9,10a,14b-hexaazadibenzo[fg, op]tetracenes via the catalytic heterocyclization of trans-1,6,7,12-tetraaza-perhydrotetracene with formaldehyde or CH2(NMe2)2 and anilines has been accomplished. Preliminary screening of thus obtained perhydro hexaazadibenzotetracenes for cytotoxic activity has been performed.
Citation:
E. B. Rakhimova, V. Yu. Kirsanov, U. Sh. Kuzmina, I. V. Galyautdinov, Yu. V. Vakhitova, “Synthesis and cytotoxic activity of new hexaazadibenzotetracenes derived from trans-1,2-diaminocyclohexane”, Mendeleev Commun., 33:1 (2023), 112–114
Linking options:
https://www.mathnet.ru/eng/mendc324
https://www.mathnet.ru/eng/mendc/v33/i1/p112
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