Abstract:
Polypeptide-based doxorubicin delivery systems were prepared and their physicochemical and functional properties, such as size, encapsulation efficiency, stability, release of doxorubicin in various media and cytotoxicity, were characterized. An in vivo study revealed an effective reduction of tumor growth when these systems were administered subcutaneously.
Citation:
N. N. Sudareva, I. I. Tarasenko, D. N. Suslov, O. M. Suvorova, K. A. Kolbe, G. Y. Yukina, M. L. Tyndyk, Yu. G. Zmitrichenko, E. G. Korzhikova-Vlakh, “Doxorubicin delivery systems based on polypeptide nanoparticles for subcutaneous administration in cancer therapy”, Mendeleev Commun., 34:1 (2024), 18–21
Linking options:
https://www.mathnet.ru/eng/mendc31
https://www.mathnet.ru/eng/mendc/v34/i1/p18
This publication is cited in the following 6 articles:
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Anjali Bisht, Dubey Avinash, Kantrol Kumar Sahu, Preeti Patel, Ghanshyam Das Gupta, Balak Das Kurmi, “A comprehensive review on doxorubicin: mechanisms, toxicity, clinical trials, combination therapies and nanoformulations in breast cancer”, Drug Deliv. and Transl. Res., 15:1 (2025), 102
Jithin Thomas, Vinay Kumar, Neha Sharma, Naomi John, Mridul Umesh, Lohith Kumar Dasarahally Huligowda, Komalpreet Kaur, Divya Utreja, “Recent approaches in nanotoxicity assessment for drug delivery applications: Challenges and prospects”, Medicine in Drug Discovery, 2025, 100204
Anastasia A. Belyaeva, Anton S. Averchuk, Nataliya A. Rozanova, Olga P. Alexandrova, Olga A. Solomakha, Yulia A. Nashchekina, Viktor A. Korzhikov-Vlakh, Stanislav O. Yurchenko, Alla B. Salmina, Evgenia G. Korzhikova-Vlakh, Sofia M. Morozova, “Thermosensitive injectable fibrillar gels based on cellulose nanocrystals grafted with poly(N-isopropylacrylamide) as biocompatible brain implants”, Carbohydrate Polymers, 346 (2024), 122596
I. I. Tarasenko, N. N. Zakharova, E. N. Vlasova, E. G. Korzhikova-Vlakh, “A novel thermoresponsive polypeptide: synthesis and characterization”, Mendeleev Commun., 34:3 (2024), 348–350
E. G. Korzhikova-Vlakh, N. N. Zashikhina, E. G. Stulova, A. Yu. Dzhuzha, V. A. Korzhikov-Vlakh, “Effect of L- or D,L-leucine content on self-assembly and properties of its amphiphilic copolymers with L-lysine”, Mendeleev Commun., 34:3 (2024), 365–368
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