Abstract:
The in situ prepared amidoximes from the reaction between nitriles and hydroxylamine are condensed with carbodiimides in the presence of molecular sieves under solvent-free conditions to produce the title compounds in excellent yields.
Document Type:
Article
Language: English
Citation:
M. Adib, Sh. Bagherzadeh, M. Mahdavi, H. R. Bijanzadeh, “An efficient one-pot synthesis of 3-aryl-1,2,4-oxadiazol-5-amines under solvent-free conditions”, Mendeleev Commun., 20:1 (2010), 50–51
Linking options:
https://www.mathnet.ru/eng/mendc2988
https://www.mathnet.ru/eng/mendc/v20/i1/p50
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P. A. Volkov, N. I. Ivanova, K. O. Khrapova, A. A. Telezhkin, T. N. Borodina, N. K. Gusarova, B. A. Trofimov, “Solvent-free synthesis of 4-chalcogenophosphorylpyridines viaSHNAr
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Marion Donnier-Maréchal, David Goyard, Vincent Folliard, Tibor Docsa, Pal Gergely, Jean-Pierre Praly, Sébastien Vidal, “3-Glucosylated 5-amino-1,2,4-oxadiazoles: synthesis and evaluation as glycogen phosphorylase inhibitors”, Beilstein J. Org. Chem., 11 (2015), 499
Robert R. P. Torregrosa, Encyclopedia of Reagents for Organic Synthesis, 2015, 1
Arif Kivrak, Metin Zora, “A novel synthesis of 1,2,4-oxadiazoles and isoxazoles”, Tetrahedron, 70:4 (2014), 817
Metin Zora, Arif Kivrak, Yilmaz Kelgokmen, “A novel one-pot synthesis of ferrocenyl-substituted 1,2,4-oxadiazoles”, Journal of Organometallic Chemistry, 759 (2014), 67
Dongshan Su, Haifeng Duan, Zhonglin Wei, Jungang Cao, Dapeng Liang, Yingjie Lin, “Condensation of Vilsmeier salts, derived from tetraalkylureas, with amidoximes: a novel approach to access N,N-dialkyl-1,2,4-oxadiazol-5-amines”, Tetrahedron Letters, 54:50 (2013), 6959
Mehdi Adib, Sharareh Bagherzadeh, Mohammad Mahdavi, Hamid R. Bijanzadeh, “ChemInform Abstract: An Efficient One‐Pot Synthesis of 3‐Aryl‐1,2,4‐oxadiazol‐5‐amines under Solvent‐Free Conditions.”, ChemInform, 41:25 (2010)
Maria Ispikoudi, Michalis Amvrazis, Christos Kontogiorgis, Alexandros E. Koumbis, Konstantinos E. Litinas, Dimitra Hadjipavlou-Litina, Konstantina C. Fylaktakidou, “Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives”, European Journal of Medicinal Chemistry, 45:12 (2010), 5635
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