Abstract:
The Bishler–Napieralski cyclodehydration of N-acyl-2-arylethylamines into the corresponding 3,4-dihydroisoquinolines with POCl3 as a dehydration reagent proceeds in ionic liquids under milder conditions and in higher yields.
Document Type:
Article
Language: English
Citation:
M. A. Epishina, A. S. Kulikov, M. I. Struchkova, N. V. Ignat'ev, M. Schulte, N. N. Makhova, “Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction”, Mendeleev Commun., 22:5 (2012), 267–269
Linking options:
https://www.mathnet.ru/eng/mendc2815
https://www.mathnet.ru/eng/mendc/v22/i5/p267
This publication is cited in the following 5 articles:
Damiano Tanini, Tommaso Pecchi, Nikolai Ignat'ev, Antonella Capperucci, “Ionic Liquids-Assisted Ring Opening of Three-Membered Heterocycles with Thio- and Seleno-Silanes”, Catalysts, 12:10 (2022), 1259
Yun-Gang He, Yong-Kang Huang, Qi-Qi Fan, Bo Zheng, Yong-Qiang Luo, Xing-Liang Zhu, Xiao-Xin Shi, “Copper(ii)-catalyzed and acid-promoted highly regioselective oxidation of tautomerizable C(sp3)–H bonds adjacent to 3,4-dihydroisoquinolines using air (O2) as a clean oxidant”, RSC Adv., 11:47 (2021), 29702
N. N. Makhova, M. I. Pleshchev, M. A. Epishina, A. S. Kulikov, “Synthesis and Transformations of Nitrogen Heterocycles in Ionic Liquids (Review)”, Chem Heterocycl Comp, 50:5 (2014), 634
A. A. Vasil'ev, S. G. Zlotin, “Palladium-catalyzed allylation of malonic acid derivatives in heterogeneous systems containing ionic liquids”, Mendeleev Commun., 24:1 (2014), 23–25
Margarita A. Epishina, Alexander S. Kulikov, Marina I. Struchkova, Nikolai V. Ignat'ev, Michael Schulte, Nina N. Makhova, “ChemInform Abstract: Ionic Liquids‐Assisted Synthesis of 3,4‐Dihydroisoquinolines by the Bishler—Napieralski Reaction.”, ChemInform, 44:11 (2013)
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